Prof. ZEYNEP ALAGÖZ

Publication Network

Articles 53

1. Antibacterial, Antifungal and Molecular Docking Studies of N1-Substituted 5-Alkylsulfonyl Benzimidazole Derivatives

Hassan M. A., Abbade Y., KIŞLA M. M., KAŞKATEPE B., ALAGÖZ Z.

Helvetica Chimica Acta , vol.108, no.10, 2025 (SCI-Expanded)

2. Rhoifolin: a promising flavonoid with cytotoxic and anticancer properties – molecular mechanisms and therapeutic potential

Kılıç C. S., Kışla M. M., Amasya Çelikten G., Şengel Türk C. T., Alagöz Z., Gençler Özkan A. M., et al.

EXCLI JOURNAL , vol.24, no.24, pp.289-320, 2025 (SCI-Expanded, Scopus)

3. ZA-II-05, a novel NMDA-receptor antagonist reverses vanadium-induced neurotoxicity in Caenorhabditis elegans (C. elegans).

Ladagu A., Olopade F., Chazot P., Elufioye T., Luong T., Fuller M., et al.

BMC neuroscience , vol.25, no.1, pp.56, 2024 (SCI-Expanded)

4. Heterocyclic Compounds as Bcr-Abl Tyrosine Kinase Inhibitors Against Chronic Myeloid Leukemia

Gado S., Hassan M. A., KIŞLA M. M., ALAGÖZ Z.

MEDICINAL CHEMISTRY , vol.21, no.7, pp.646-665, 2024 (SCI-Expanded, Scopus) Sustainable Development

5. Targeting Bcl-2 with Indole Scaffolds: Emerging Drug Design Strategies for Cancer Treatment

Zarrin P., ALAGÖZ Z.

MINI-REVIEWS IN MEDICINAL CHEMISTRY , vol.25, no.4, pp.293-318, 2024 (SCI-Expanded, Scopus) Sustainable Development

6. Synthesis and Structure of Novel Phenothiazine Derivatives, and Compound Prioritization via In Silico Target Search and Screening for Cytotoxic and Cholinesterase Modulatory Activities in Liver Cancer Cells and In Vivo in Zebrafish

KIŞLA M. M., Yaman M., Zengin-Karadayi F., Korkmaz B., Bayazeid O., Kumar A., et al.

ACS OMEGA , vol.9, no.28, pp.30594-30614, 2024 (SCI-Expanded, Scopus)

7. **Synthesis, Anticancer Activity, and In Silico Modeling of Alkylsulfonyl Benzimidazole Derivatives: Unveiling Potent Bcl-2 Inhibitors for Breast Cancer**

Abbade Y., KIŞLA M. M., Hassan M. A., ÇELİK İ., Dogan T. S., MUTLU P., et al.

ACS OMEGA , vol.9, no.8, pp.9547-9563, 2024 (SCI-Expanded, Scopus)

8. Pioneering the Battle Against Breast Cancer: The Promise of New Bcl-2 Family

Boroujeni A. F., ALAGÖZ Z.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY , vol.25, no.3, pp.164-178, 2024 (SCI-Expanded, Scopus) Sustainable Development

9. Cyclin-Dependent Kinase 4/6 Inhibitors Against Breast Cancer

Hassan M. A., Alagöz Z.

Mini reviews in medicinal chemistry , vol.23, no.4, pp.412-428, 2023 (SCI-Expanded)

10. Benzimidazoles Against Certain Breast Cancer Drug Targets: A Review

KIŞLA M. M., ALAGÖZ Z.

MINI-REVIEWS IN MEDICINAL CHEMISTRY , vol.22, no.19, pp.2463-2477, 2022 (SCI-Expanded, Scopus)

11. RNA-DEPENDENT RNA POLYMERASE (RDRP) INHIBITOR DRUGS AGAINST SARS-COV-2: A MOLECULAR DOCKING STUDY SARS-COV-2'YE KARŞI RNA-BAĞIMLI RNA POLİMERAZ (RDRP) İNHİBİTÖR İLAÇLARI: BİR MOLEKÜLER DOCKİNG ÇALIŞMASI

Gado S., ALAGÖZ Z.

Ankara Universitesi Eczacilik Fakultesi Dergisi , vol.46, no.1, pp.62-77, 2022 (Scopus)

12. Synthesis, antioxidant activity, molecular docking and ADME studies of novel pyrrole-benzimidazole derivatives

Zengin Karadayi F., Basaran R., Kişla M. M., Eke B., Alagöz Z.

TURKISH JOURNAL OF CHEMISTRY , vol.46, no.3, pp.890-921, 2022 (SCI-Expanded, Scopus, TRDizin)

13. Design, synthesis, molecular docking and ADME studies of novel indole-thiazolidinedione derivatives and their antineoplastic activity as CDK6 inhibitors

Ates-Alagoz Z., KIŞLA M. M., Karadayi F. Z., Baran S., DOĞAN T., MUTLU P.

NEW JOURNAL OF CHEMISTRY , vol.45, no.38, pp.18025-18038, 2021 (SCI-Expanded, Scopus)

14. Design, synthesis, anticancer activity, molecular docking and ADME studies of novel methylsulfonyl indole-benzimidazoles in comparison with ethylsulfonyl counterparts

Karadayi F. Z., Yaman M., KIŞLA M. M., KONU KARAKAYALI Ö., Ates-Alagoz Z.

NEW JOURNAL OF CHEMISTRY , vol.45, no.20, pp.9010-9019, 2021 (SCI-Expanded, Scopus)

15. Synthesis, Molecular Docking Studies and Antibacterial Activities of Novel Monocationic Indole-benzimidazole Derivatives

Ates-Alagoz Z., KIŞLA M. M., Goker H., Yildiz S.

MEDICINAL CHEMISTRY , vol.17, no.7, pp.699-706, 2021 (SCI-Expanded, Scopus)

16. Design, synthesis and anticancer/antiestrogenic activities of novel indole- benzimidazoles

Karadayi F. Z., Yaman M., KIŞLA M. M., Keskus A. G., KONU KARAKAYALI Ö., Ates-Alagoz Z.

BIOORGANIC CHEMISTRY , vol.100, 2020 (SCI-Expanded, Scopus)

17. Bicycloheptylamine-Doxorubicin Conjugate: Synthesis and Anticancer Activities in sigma(2) Receptor-Expressing Cell Lines

Alamri M. A., Ates-Alagoz Z., Adejare A.

MEDICINAL CHEMISTRY , vol.16, no.2, pp.192-201, 2020 (SCI-Expanded, Scopus)

18. YENİ TETRAHİDRONAFTALEN-BENZİMİDAZOL TÜREVİ BİLEŞİKLERİN MOLEKÜLERDOKİNG ÇALIŞMALARI VE ONLARIN ANTİ-MRSA AKTİVİTELERİNİNKARŞILAŞTIRILMASI

ZENGİN F., KIŞLA M. M., ALAGÖZ Z.

Ankara Üniversitesi Eczacılık Fakültesi Dergisi , 2019 (Scopus)

19. Molecular docking studies of some tetrahydronaphtalene-benzimidazole derivatives and correlation with their corresponding anti-MRSA activities

Zengin F., KIŞLA M. M., ALAGÖZ Z.

Ankara Universitesi Eczacilik Fakultesi Dergisi , vol.43, no.1, pp.20-27, 2019 (Scopus)

20. Physicochemical Properties for Potential Alzheimer's Disease Drugs

ALAGÖZ Z., Adejare A.

DRUG DISCOVERY APPROACHES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS: ALZHEIMER'S DISEASE , pp.59-82, 2017 (SCI-Expanded)

21. Bicycloheptylamines and cyclohexylamines as sigma 2 receptor ligands: Potential use as anticancer agents

Alamri M., ALAGÖZ Z., Adejare A.

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY , vol.252, 2016 (SCI-Expanded)

22. Anticarcinogenic effects of curcumin and it's analogs Kurkumin ve analoglarinin antikanserojen etkileri

Toptaş B., ALAGÖZ Z.

Ankara Universitesi Eczacilik Fakultesi Dergisi , vol.40, no.2, pp.58-82, 2016 (Scopus) Sustainable Development

23. Antimicrobial Activities of 1-H-Benzimidazole-based Molecules

ALAGÖZ Z.

CURRENT TOPICS IN MEDICINAL CHEMISTRY , vol.16, no.26, pp.2953-2962, 2016 (SCI-Expanded, Scopus) Sustainable Development

24. Genotoxicity studies of tetrahydro-naphthalene-benzimidazole/thiazolidinedione as retinoid derivatives

DOĞAN T., Durusoy M., ALAGÖZ Z., Buyukbingol E.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI , vol.40, no.6, pp.500-507, 2015 (SCI-Expanded)

25. Antioxidant Activities of Retinoidal Benzimidazole Or Indole Derivatives in In Vitro Model Systems

ALAGÖZ Z.

CURRENT MEDICINAL CHEMISTRY , vol.20, no.36, pp.4633-4639, 2013 (SCI-Expanded, Scopus)

26. Systematic Structure Modifications of Multitarget Prostate Cancer Drug Candidate Galeterone To Produce Novel Androgen Receptor Down-Regulating Agents-as an Approach to Treatment of Advanced Prostate Cancer

Purushottamachar P., Godbole A. M., Gediya L. K., Martin M. S., Vasaitis T. S., Kwegyir-Afful A. K., et al.

JOURNAL OF MEDICINAL CHEMISTRY , vol.56, no.12, pp.4880-4898, 2013 (SCI-Expanded, Scopus)

27. Toxicity studies on novel N-substituted bicyclo-heptan-2-amines at NMDA receptors

Coleman N., ALAGÖZ Z., Gaye B., Farbaniec M., Sun S., Adejare A.

Pharmaceuticals , vol.6, no.4, pp.536-545, 2013 (Scopus)

28. NMDA Receptor Antagonists for Treatment of Depression

ALAGÖZ Z., Adejare A.

PHARMACEUTICALS , vol.6, no.4, pp.480-499, 2013 (ESCI, Scopus)

29. Syntheses and In Vitro Anticancer Properties of Novel Radiosensitizers

ALAGÖZ Z., Coleman N., Martin M., Wan A., Adejare A.

CHEMICAL BIOLOGY & DRUG DESIGN , vol.80, no.6, pp.853-861, 2012 (SCI-Expanded, Scopus) Sustainable Development

30. Synthesis and biological evaluations of putative metabolically stable analogs of VN/124-1 (TOK-001): Head to head anti-tumor efficacy evaluation of VN/124-1 (TOK-001) and abiraterone in LAPC-4 human prostate cancer xenograft model

Bruno R. D., Vasaitis T. S., Gediya L. K., Purushottamachar P., Godbole A. M., ALAGÖZ Z., et al.

STEROIDS , vol.76, no.12, pp.1268-1279, 2011 (SCI-Expanded, Scopus)

31. Syntheses and Pharmacological Evaluations of Novel N-Substituted Bicyclo-Heptane-2-amines at N-Methyl-D-Aspartate Receptors

ALAGÖZ Z., Sun S., Wallach J., Adejare A.

CHEMICAL BIOLOGY & DRUG DESIGN , vol.78, no.1, pp.25-32, 2011 (SCI-Expanded, Scopus)

32. Roles of NMDA receptor antagonists in neuropathic pain NMDA reseptör antagoni̇stleri̇ni̇n nöropati̇k aǧridaki̇ rolleri̇

Atila S., ALAGÖZ Z.

Ankara Universitesi Eczacilik Fakultesi Dergisi , vol.39, no.1, pp.51-68, 2010 (Scopus)

33. Synthesis and Antimicrobial Activity of New Tetrahydro-Naphthalene-Thiazolidinedione and Thiohydantoine Derivatives

ALAGÖZ Z., Altanlar N., Buyukbingol E.

JOURNAL OF HETEROCYCLIC CHEMISTRY , vol.46, no.6, pp.1375-1379, 2009 (SCI-Expanded, Scopus)

34. Synthesis and Potent Antifungal Activity Against Candida Species of Some Novel 1H-Benzimidazoles

GÖKER A. H., ALP M., ALAGÖZ Z., Yildiz S.

JOURNAL OF HETEROCYCLIC CHEMISTRY , vol.46, no.5, pp.936-948, 2009 (SCI-Expanded, Scopus)

35. Synthesis and antimicrobial evaluation of some new substituted purine derivatives

TUNÇBİLEK M., ALAGÖZ Z., ALTANLAR N., Karayel A., ÖZBEY S.

BIOORGANIC & MEDICINAL CHEMISTRY , vol.17, no.4, pp.1693-1700, 2009 (SCI-Expanded, Scopus)

36. DNA Binding and Antiproliferative Effects of Some Benzimidazole Retinoids

Piskin A. K., ALAGÖZ Z., ATAÇ F. B., MUŞDAL Y., Buyukbingol E.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI , vol.34, no.1, pp.39-43, 2009 (SCI-Expanded, Scopus, TRDizin)

37. Antimicrobial activities of some tetrahydronaphthalene-benzimidazole derivatives

ALAGÖZ Z., Yildiz S., Buyukbingo E.

CHEMOTHERAPY , vol.53, no.2, pp.110-113, 2007 (SCI-Expanded, Scopus)

38. Synthesis and antioxidant activity of new tetrahydro-naphthalene-indole derivatives as retinoid and melatonin analogs

ALAGÖZ Z., Coban T., Buyukbingol E.

Archiv der Pharmazie , vol.339, no.4, pp.193-200, 2006 (SCI-Expanded, Scopus) Sustainable Development

39. Synthesis and potent antimicrobial activities of some novel retinoidal monocationic benzimidazoles

ALAGÖZ Z., Alp M., Kus C., Yildiz S., Buyukbingol E., GÖKER A. H.

Archiv der Pharmazie , vol.339, no.2, pp.74-80, 2006 (SCI-Expanded, Scopus)

40. A comparative study: Evaluation of antioxidant activity of melatonin and some indole derivatives

ALAGÖZ Z., Coban T., Suzen S.

Medicinal Chemistry Research , vol.14, no.3, pp.169-179, 2005 (SCI-Expanded, Scopus)

41. Structure-activity relationships of antioxidant effective some melatonin derivatives Anti̇oksi̇dan etki̇li̇ melatoni̇n türevi̇ bazi bi̇leşi̇kleri̇n yapi-etki̇ i̇li̇şki̇ leri̇

ALAGÖZ Z.

Ankara Universitesi Eczacilik Fakultesi Dergisi , vol.34, no.2, pp.73-93, 2005 (Scopus)

42. Genotoxicity studies on benzimidazole retinoids

Balaban F., ALAGÖZ Z., Buyukbingol E., Iscan M.

PHARMAZIE , vol.60, no.11, pp.861-868, 2005 (SCI-Expanded, Scopus)

43. Synthesis and antioxidant properties of some indole ethylamine derivatives as melatonin analogs

ALAGÖZ Z., Buyukbingol Z., Buyukbingol E.

PHARMAZIE , vol.60, no.9, pp.643-647, 2005 (SCI-Expanded, Scopus)

44. Synthesis and antioxidant properties of novel benzimidazoles containing substituted indole or 1,1,4,4-tetramethyl-1,2,3,4-tetrahydro-naphthalene fragments

ALAGÖZ Z., Kus C., Coban T.

Journal of Enzyme Inhibition and Medicinal Chemistry , vol.20, no.4, pp.325-331, 2005 (SCI-Expanded, Scopus)

45. Antioxidant properties of novel benzimidazole retinoids

ALAGÖZ Z., Can-Eke B., Coban T., Iscan M., Buyukbingol E.

Archiv der Pharmazie , vol.337, no.4, pp.188-192, 2004 (SCI-Expanded, Scopus)

46. Oxidative damage in the central nervous system and protection by melatoni̇n Santral si̇ni̇r si̇stemi̇ni̇n oksi̇dati̇f hasari ve melatoni̇n tarafindan korunmasi

ALAGÖZ Z., SÜZEN S.

Ankara Universitesi Eczacilik Fakultesi Dergisi , vol.30, no.3, pp.47-62, 2001 (Scopus)

47. Crystal structure of 2-[(5 ',6 ',7 ',8 '-tetrahydro-5 ',5 ',8 ',8 '-tetramethyl)-2 '-naphthyl]-1-ethyl-1H-benzimidazole-5-carboxylic acid ethyl ester

Kendi E., ALAGÖZ Z., Suzen S., Buyukbingol E.

ANALYTICAL SCIENCES , vol.17, no.4, pp.567-568, 2001 (SCI-Expanded)

48. Synthesis and analytical evaluation by voltammetric studies of some new indole-3-propionamide derivatives

Suzen S., ALAGÖZ Z., Demircigil B., Ozkan S. A.

Farmaco , vol.56, no.11, pp.835-840, 2001 (SCI-Expanded, Scopus)

49. Structure activity relationships of melatonin analogues

ALAGÖZ Z., SÜZEN S.

Ankara UniversitesiEczacilik Fakultesi Dergisi. , vol.30, no.4, pp.41-52, 2001 (Scopus)

50. Synthesis of some novel tetrahydronaphthalene benzimidazole derivatives

Ates-Alayoz Z., Buyukbingol E.

Heterocyclic Communications , vol.7, no.5, pp.455-460, 2001 (SCI-Expanded, Scopus)

51. Oxidative damage in the central nervous system and protection by melatoni n

ALAGÖZ Z., SÜZEN S.

Ankara Universitesi Eczacilik FakultesiDergisi , vol.30, no.3, pp.47-62, 2001 (Scopus)

52. Synthesis and structure of 2-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalene)]-5-benzimidazole ethylcarboxylate monohydrate

ALAGÖZ Z., Suzen S., Buyukbingol E., Caira M.

JOURNAL OF CHEMICAL CRYSTALLOGRAPHY , vol.30, no.2, pp.103-107, 2000 (SCI-Expanded, Scopus)

53. Antioxidant activities of indole and benzimidazole derivatives

SÜZEN S., ALAGÖZ Z., Puskullu M.

Fabad Journal of Pharmaceutical Sciences , vol.25, no.3, pp.113-119, 2000 (Scopus) Sustainable Development

Papers Presented at Peer-Reviewed Scientific Conferences 17

1. FENOTİYAZİN TÜREVİ BİLEŞİKLERİN SENTEZLERİ, ANTİKANSER AKTİVİTELERİ VE MOLEKÜLER DOKİNG ANALİZLERİ

KIŞLA M. M., Yaman M., KONU KARAKAYALI Ö., ALAGÖZ Z.

VI. Ulusal Farmasötik Kimya Kongresi, 26–29 Ağustos 2022, İstanbul, İstanbul, Turkey, 26 - 29 August 2022, (Full Text)

2. SYHTHESIS, ANTINEOPLASTIC ACTIVITY AND MOLECULAR DOCKING STUDIES OF NOVEL INDOLE- THIAZOLIDINEDIONE DERIVATIVES

KIŞLA M. M., Zengin Karadayı F., DOĞAN T., MUTLU P., ALAGÖZ Z., Baran S.

13 th International Symposium on Pharmaceutical Sciences, Ankara, Turkey, 22 - 25 June 2021, (Summary Text)

3. Molecular, biochemical and in silico analyses of commercial and novel phenothiazines as anticancer agents

Yaman M., Tiryaki S., Zengin Karadayi F., KIŞLA M. M., Omer B., Keskus A. G., et al.

12th International Symposium on Pharmaceutical Sciences (ISOPS), Ankara, Turkey, 26 - 29 June 2018, (Summary Text)

4. SYNTHESES AND ANTIMICROBIAL ACTIVITIES OF NOVEL MONOCATIONIC INDOLE-BENZIMIDAZOLE DERIVATIVES

ALAGÖZ Z., YILDIZ S., GÖKER A. H.

12 th International Symposium on Pharmaceutical Sciences, 26 - 29 June 2018, (Summary Text)

5. Design, Syntheses and Structure Identification of Novel Monocationic Indole-Benzimidazole Derivatives

ALAGÖZ Z., GÖKER A. H.

WASET 19. world academy of science, engineering and technology conference program, Italy, 21 - 22 June 2017, (Summary Text)

6. Syntheses and Antioxidant Activity of Novel Pyrrol-Benzoimidazole Derivatives

ALAGÖZ Z., Zengin F., Başaran R., Can Eke B.

8th World Congress on Toxicology and Pharmacology, 13 - 15 April 2017, (Summary Text)

7. Ankara University Faculty Of Pharmacy Workshop Results Of Graduates

ALAGÖZ Z., ÖZÇELİKAY G.

22nd EAFP Annual Conference, Châtenay-Malabry, France, 12 - 14 May 2016

8. Ankara Üniversitesi Eczacılık Fakültesinin Tarihçesi Eğitim Olanakları Stajlar Meslek İçi Eğitim Programları ve Öğrencilerimizin İş Olanakları

ÖZÇELİKAY G., ALAGÖZ Z.

I. Ulusal Eczacılık Eğitimi ve Akreditasyon Kongresi, Ankara, Turkey, 9 - 10 May 2016

9. Identification of Novel Indole benzimidazole Compounds with Antiproliferative and Ion Channel Modulatory Effects

KONU KARAKAYALI Ö., YAMAN M., ZENGİN F., ALAGÖZ Z.

5th RSC / SCI symposium on Ion Channels as Therapeutic Targets, Cambridge, Canada, 14 - 15 March 2016

10. Screening Of Anticancer Activity And In Vivo Toxicity Of Novel Indolebenzimidazole Ethylsulfonyl Derivatives

ALAGÖZ Z., YAMAN M., ZENGİN F., BAYDIN T., KONU KARAKAYALI Ö.

The 9th European Zebrafish Meeting, Oslo, Norway, 28 June - 02 July 2015

11. Design Syntheses And Antıcancer Activity Of 5 Alkylsulfonyl 2 5 subs 1H indol 3 il 1 subs 1H Benzo d imidazoles

ZENGİN F., YAMAN M., ALAGÖZ Z., KONU KARAKAYALI Ö.

GPSS-1 st International Gazi Pharma Symposium Series, Antalya, Turkey, 12 - 15 November 2015

12. Bicycloheptylamines and Cyclohexylamines as 2 Receptor Ligands Potential Use as AnticancerAgents

ALAMRİ M., ALAGÖZ Z., ADEJARE A.

2015 AAPS Annual Meeting and Exposition, ORLANDO, United States Of America, 25 - 29 October 2015

13. Synthesis structure identification and biological evaluation of novel indole alkyl sulfonyl benzimidazoles

ZENGİN F., ALAGÖZ Z.

11th International Symposium on Pharmaceutical Sciences (ISOPS-11), 9 - 12 June 2015

14. Syntheses And Antıcancer Activity Of Novel Indole Benzimidazole Derivatives

IŞIK Ç., ÖZDEMİR S., KONU KARAKAYALI Ö., ALAGÖZ Z.

11th International Symposium on Pharmaceutical Sciences (ISOPS-11), Ankara, Turkey, 9 - 12 June 2015

15. Synthesis and biological evaluation of novel indole benzimidazole ethylsulfonyl derivatives as potential anticancer agents

ALAGÖZ Z., ZENGİN F., YAMAN M., KONU KARAKAYALI Ö.

11th International Symposium on Pharmaceutical Sciences (ISOPS-11), Ankara, Turkey, 9 - 12 June 2015

16. Antioxidant properties of novel NMDA receptor antagonists and radiosensitizers

Nguyen Q. N., Gaye B. T., ALAGÖZ Z., Wallach J. V., Adejare A.

244th National Fall Meeting of the American-Chemical-Society (ACS), Pennsylvania, United States Of America, 19 - 23 August 2012, vol.244, (Summary Text)

17. Exploitation of multitarget prostate cancer clinical candidate VN/124-1 (TOK-001) to develop a novel class of androgen receptor down regulating agents for prostate cancer therapy

Puranik P. P., Godbole A. M., Gediya L. K., ALAGÖZ Z., Njar V. C. O.

242nd National Meeting of the American-Chemical-Society (ACS), Colorado, United States Of America, 28 August - 01 September 2011, vol.242, (Summary Text)

Books 12

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