Synthesis and structure of 2-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalene)]-5-benzimidazole ethylcarboxylate monohydrate

ALAGÖZ Z., Suzen S., Buyukbingol E., Caira M.

JOURNAL OF CHEMICAL CRYSTALLOGRAPHY, cilt.30, sa.2, ss.103-107, 2000 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 2
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1023/a:1009565512076
  • Dergi Adı: JOURNAL OF CHEMICAL CRYSTALLOGRAPHY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.103-107
  • Anahtar Kelimeler: retinoic acid analog, benzimidazole, anticarcinogenic/antioxidant, RETINOIDS
  • Ankara Üniversitesi Adresli: Evet

Özet

As part of a program investigating the conformations of potential anticarcinogens and antioxidants, the structure of the title compound C24H28N2O2. H2O is reported. The monohydrate crystallizes in the monoclinic space group P2/c with unit cell parameters a = 16.184(1), b = 7.937(1), c = 16.968(1), beta = 92.788(7)degrees and Z = 4. The benzimidazole and tetrahydro-tetramethylnaphthalene ring systems are inclined to one another by approximately 26 degrees. The water molecule plays an important role in the crystal structure by hydrogen bonding to different functional groups of three organic moieties. Additional crystal stabilization is due to pi-pi stacking of benzimidazole rings.