Prof. Dr. TUNCAGÜL ALTUNTAŞ

Yayın Ağı

Makaleler 30

1. Design, synthesis, and biological evaluation of novel amidoxime or amidine analogues of some 4-anilino-6,7-dimethoxyquinazolines with a potent EGFR inhibitory effect

Acar Halıcı C., Göker H., Kütük Ö., ÇELİK İ., ALTUNTAŞ T.

Bioorganic Chemistry , cilt.158, 2025 (SCI-Expanded)

2. Novel indole hydrazide derivatives: Synthesis and their antiproliferative activities through inducing apoptosis and DNA damage

KILIÇ KURT Z., Acar C., ERGÜL M., BAKAR ATEŞ F., Altuntas T.

ARCHIV DER PHARMAZIE , cilt.353, sa.8, 2020 (SCI-Expanded, Scopus)

3. Novel piperazine substituted indole derivatives: Synthesis, anti-inflammatory and antioxidant activities and molecular docking

Altuntas T., Baydar A., KILIÇ KURT Z., Acar C., YILMAZ SARIALTIN S., ÇOBAN T.

JOURNAL OF RESEARCH IN PHARMACY , cilt.24, sa.3, ss.350-360, 2020 (ESCI, Scopus, TRDizin)

4. Hedefe Yönelik Kanser Tedavisinde Kullanılan Akıllı İlaçlar: EGFR İnhibitörleri

Acar C., ALTUNTAŞ T.

Fabad Journal of Pharmaceutical Sciences , cilt.44, sa.1, ss.47-63, 2019 (Scopus) Sürdürülebilir Kalkınma

5. In Vitro Antibacterial and Antifungal Activity and Computational Evaluation of Novel Indole Derivatives Containing 4-substituted Piperazine Moieties

ALTUNTAŞ T., Yilmaz N., Ece A., ALTANLAR N., ÖLGEN S.

LETTERS IN DRUG DESIGN & DISCOVERY , cilt.15, sa.10, ss.1079-1086, 2018 (SCI-Expanded, Scopus)

6. Synthesis and Antioxidant Activity of Indole Derivatives Containing 4-Substituted Piperazine Moieties

ALTUNTAŞ T., Yilmaz N., ÇOBAN T., ÖLGEN S.

LETTERS IN DRUG DESIGN & DISCOVERY , cilt.14, sa.4, ss.380-386, 2017 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

7. Role of cytochrome P4503A in cysteine S-conjugates sulfoxidation and the nephrotoxicity of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A) in rats

Sheffels P., Schroeder J., ALTUNTAŞ T., Liggitt H., Kharasch E.

CHEMICAL RESEARCH IN TOXICOLOGY , cilt.17, sa.9, ss.1177-1189, 2004 (SCI-Expanded, Scopus)

8. Comparison of derivative spectrophotometric and liquid chromatographic methods for the determination of rofecoxib

Erk N., ALTUNTAŞ T.

PHARMAZIE , cilt.59, sa.6, ss.453-456, 2004 (SCI-Expanded, Scopus)

9. Sulfoxidation of cysteine and mercapturic acid conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (Compound A)

ALTUNTAŞ T., Park S., Kharasch E.

CHEMICAL RESEARCH IN TOXICOLOGY , cilt.17, sa.3, ss.435-445, 2004 (SCI-Expanded, Scopus)

10. Quinidine as a probe for the role of P-glycoprotein in the intestinal absorption and clinical effects of fentanyl

Kharasch E., Hoffer C., ALTUNTAŞ T., Whittington D.

JOURNAL OF CLINICAL PHARMACOLOGY , cilt.44, sa.3, ss.224-233, 2004 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

11. Liquid chromatographic determination of atorvastatin in bulk drug, tablets, and human plasma

ALTUNTAŞ T., Erk N.

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES , cilt.27, sa.1, ss.83-93, 2004 (SCI-Expanded, Scopus)

12. A study on the interaction between p60(c-Src) receptor tyrosine kinase and arylcarboxylic and arylacetic acid derivatives based on docking modes and in vitro activity

ALTUNTAŞ T., Olgen S., Nebioglu D., Akaho E.

BIOLOGICAL & PHARMACEUTICAL BULLETIN , cilt.27, sa.1, ss.61-65, 2004 (SCI-Expanded, Scopus)

13. Cytotoxicity of S-conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl) vinyl ether (Compound A) in a human proximal tubular cell line

ALTUNTAŞ T., Zager R., Kharasch E.

TOXICOLOGY AND APPLIED PHARMACOLOGY , cilt.193, sa.1, ss.55-65, 2003 (SCI-Expanded, Scopus)

14. Biotransformation of L-cysteine S-conjugates and N-acetyl-L-cysteine S-conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A) in human kidney in vitro: Interindividual variability in N-acetylation, N-deacetylation, and beta-lyase-catalyzed metabolism

ALTUNTAŞ T., Kharasch E.

DRUG METABOLISM AND DISPOSITION , cilt.30, sa.2, ss.148-154, 2002 (SCI-Expanded, Scopus)

15. Glutathione S-conjugation of the sevoflurane degradation product, fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A) in human liver, kidney, and blood in vitro

ALTUNTAŞ T., Kharasch E.

TOXICOLOGY AND APPLIED PHARMACOLOGY , cilt.177, sa.2, ss.85-93, 2001 (SCI-Expanded, Scopus)

16. Determination of tetrahydrozoline hydrochloride and fluorometholone in pharmaceutical formulations by HPLC and derivative UV spectrophotometry

ALTUNTAŞ T., Korkmaz F., Nebioglu D.

PHARMAZIE , cilt.55, sa.1, ss.49-52, 2000 (SCI-Expanded, Scopus)

17. Quantitative determination of acrivastine and pseudoephedrine hydrochloride in pharmaceutical formulation by high performance liquid chromatography and derivative spectrophotometry

ALTUNTAŞ T., Zanooz S., Nebioglu D.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS , cilt.17, sa.1, ss.103-109, 1998 (SCI-Expanded, Scopus)

18. Comutagenesis .3. In vitro metabolism of 2-amino-3-methylpyridine: the effect of various potential inhibitors, activators and inducers

ALTUNTAŞ T., Gorrod J.

XENOBIOTICA , cilt.27, sa.11, ss.1103-1111, 1997 (SCI-Expanded, Scopus)

19. Comutagenesis-IV in vitro metabolism of the comutagen 2-amino-3-methylpyridine: Species differences and metabolic interaction with norharman

ALTUNTAŞ T., Gorrod J.

ANTICANCER RESEARCH , cilt.17, sa.6D, ss.4479-4482, 1997 (SCI-Expanded, Scopus)

20. Comutagenesis-V: rapid conversion of 2-hydroxylamino-3-methylpyridine to 2-amino-3-methylpyridine by a hepatic S9 preparation

Gorrod J., ALTUNTAŞ T.

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS , cilt.22, sa.4, ss.341-344, 1997 (SCI-Expanded, Scopus)

21. Comutagenesis-I: The in vitro metabolism of 2-amino-3-methylpydidine

ALTUNTAŞ T., Manson D., Zhao K., Gorrod J.

ANTICANCER RESEARCH , cilt.17, sa.5A, ss.3485-3491, 1997 (SCI-Expanded, Scopus)

22. Comutagenesis-I: The in vitro metabolism of 2-amino-3-methylpyridine

ALTUNTAŞ T., Manson D., Zhao K., Gorrod J. W.

Anticancer Research , cilt.17, sa.5 A, ss.3485-3491, 1997 (SCI-Expanded)

23. Comutagenesis-II some factors influencing the in vitro metabolism of 2- amino-3-methylpyridine

ALTUNTAŞ T., Gorrod J.

Drug Metabolism and Drug Interactions , cilt.13, sa.4, ss.271-283, 1997 (Scopus)

24. Effect of various potential inhibitors, activators and inducers on the N-oxidation of isomeric aromatic diazines in vitro using rabbit liver microsomal preparations

ALTUNTAŞ T., Gorrod J.

XENOBIOTICA , cilt.26, sa.1, ss.9-15, 1996 (SCI-Expanded, Scopus)

25. Factors involved in the N-oxidation of isomeric aromatic diazines by microsomal preparations

ALTUNTAŞ T., Gorrod J. W.

Drug Metabolism and Drug Interactions , cilt.12, sa.2, ss.117-130, 1995 (Scopus)

26. The in vitro oxidation of isomeric aromatic diazines to mono-N-oxides

ALTUNTAŞ T., Gorrod J.

Pharmaceutical Science Communications , cilt.4, sa.2, ss.117-124, 1994 (Scopus)

27. CYTOCHROME-P450 INVOLVEMENT IN THE MICROSOMAL OXIDATION OF ISOMERIC DIAZINES TO MONO-N-OXIDES

GORROD J., ALTUNTAŞ T.

FASEB JOURNAL , cilt.8, sa.7, 1994 (SCI-Expanded)

28. Studies on the quantitative analysis methods for diclofenac sodium in pharmaceutical preparation

ALTUNTAŞ DİNLENÇ T., NEBİOĞLU M. D.

Pharmacia-JTPA , cilt.32, ss.1-11, 1992 (Hakemli Dergi)

29. INVITRO TUBERCULOSTATIC ACTIVITIES OF SOME 2-BENZYLBENZIMIDAZOLE AND 2-PHENOXYMETHYLBENZIMIDAZOLE DERIVATIVES

GUMUS F., ALTUNTAŞ T., SAYGUN N., OZDEN T., OZDEN S.

JOURNAL DE PHARMACIE DE BELGIQUE , cilt.44, sa.6, ss.398-402, 1989 (SCI-Expanded)

30. Cephalosporines and new antibiotics of cephalosporine derivatives

Ozden S., ALTUNTAŞ DİNLENÇ T.

A.U. Eczacilik Fakultesi Yayinlari , cilt.60, ss.155-162, 1986 (Hakemli Dergi)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 20

1. Preparation and Antioxidant Activity of Heterocyclic Indole Serivatives

ALTUNTAŞ DİNLENÇ T., Baydar A., ACAR C., YILMAZ SARIALTIN S., ÇOBAN T.

ICDDMCCP 2018: 20th International Conference on Drug Design, Medicinal Chemistry and Clinical Pharmacy, Londrina, Brezilya, 26 - 27 Temmuz 2018, (Özet Bildiri)

2. Determination of risperidone and 9-hydroxyrisperidone in human plasma by LC-MS

ALTUNTAŞ DİNLENÇ T., Demiray Yıldırm G.

International Symposium on Pharmaceutical Sciences (ISOPS-12), Ankara, Türkiye, 26 - 29 Haziran 2018, (Özet Bildiri)

3. In vitro anti-inflammatory activity of novel 5-fluoro and 5-methoxy indole-piperazine derivatives

ALTUNTAŞ DİNLENÇ T., BAYDAR A., YILMAZ SARIALTIN S., ÇOBAN T.

12th International Symposium on Pharmaceutical Sciences, Ankara, Türkiye, 26 - 29 Haziran 2018, (Özet Bildiri)

4. Synthesis of some 6,7 dimethoxy quinazoline derivatives as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors

ACAR C., ALTUNTAŞ DİNLENÇ T., GÖKER A. H.

International Symposium on Pharmaceutical Sciences (ISOPS-12), Ankara, Türkiye, 26 - 29 Haziran 2018, (Özet Bildiri)

5. Anti-inflammatory Activity of Indole Derivatives Containing 4-Substituted Piperazine Moieties

ALTUNTAŞ DİNLENÇ T., YILMAZ SARIALTIN S., ÇOBAN T.

International Eurasian Conference on Biological and Chemical Sciences (EurasianBiochem 2018), Ankara, Türkiye, 26 - 27 Nisan 2018, (Özet Bildiri)

6. Synthesis and Antioxidant Activity of Indole Derivatives Containing 4 Substituted Piperazine Moieties

ALTUNTAŞ DİNLENÇ T., YILMAZ N., ÇOBAN T., KILIÇ Z., ÖLGEN S.

11th International Symposiumon Pharmaceutical Sciences, Ankara, Türkiye, 9 - 12 Haziran 2015, (Tam Metin Bildiri)

7. Synthesis of 4-N-substituted piperazine derivatives containing indole-2-carboxylic acid’

ALTUNTAŞ DİNLENÇ T., Baydar A., KILIÇ KURT Z.

International Symposium on Pharmaceutical Sciences (ISOPS-11), Ankara, Türkiye, 9 - 12 Haziran 2015, (Özet Bildiri)

8. Indole Containing Heteroaryl Piperazine Derivatives

ALTUNTAŞ DİNLENÇ T., Akansoy N.

RICT 2011 (The 47th International Conference on Medicinal Chemistry), Lyon, Fransa, 6 - 08 Temmuz 2011, (Özet Bildiri)

9. Antioxidant Activity of Some Amide Derivatives of Diclofenac as Prodrugs

ALTUNTAŞ T., ÇOBAN T., Sener F.

9th International Meeting of the International-Society-for-the-Study-of-Xenobiotics(ISSX), İstanbul, Türkiye, 4 - 08 Eylül 2010, cilt.42, ss.100-101, (Özet Bildiri)

10. Synthesis of Indole Containing Heteroaryl Piperazine Derivatives as Reverse Transcriptase Inhibitors.

ALTUNTAŞ DİNLENÇ T., Akansoy N.

ICOS-18 (18th International Conference on Organic Synthesis), Bergen, Norveç, 1 - 06 Ağustos 2010, (Özet Bildiri)

11. Interindividual variability in N-acetylation, N-deacetylation, and ß-lyase-catalyzed metabolism of S-conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether in human kidney in vıtro

ALTUNTAŞ DİNLENÇ T., Kharasch E.

7th International Symposium on Pharmaceutical Sciences (ISOPS-7), Ankara, Türkiye, 24 - 27 Haziran 2003, (Özet Bildiri)

12. Sulfoxidation of cysteine and mercapturic acid conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether

ALTUNTAŞ T., Park S., Kharasch E.

9th European ISSX Meeting, Nice, Fransa, 12 - 17 Haziran 2005, cilt.37, ss.27, (Özet Bildiri)

13. The role of cytochrome P4503A4/5 in sulfoxidation of cysteine S-conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether

ALTUNTAŞ DİNLENÇ T., Sheffels P., Schroeder J., Kharasch E.

7th International ISSX Meeting, Vancouver, Kanada, 29 Ağustos - 02 Eylül 2004, cilt.36, (Özet Bildiri)

14. The role of cytochrome P4503A4/5 in sulfoxidation of S-conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether

ALTUNTAŞ T., Sheffels P., Schroeder J., Kharasch E.

7th European ISSX Meeting, Vancouver, Kanada, 29 Ağustos - 02 Eylül 2004, cilt.36, ss.193, (Özet Bildiri)

15. A study on the interaction between p60c-Src receptor tyrosine kinase and arylcarboxylic and arylacetic acid derivatives based on docking modes and in vitro bioactivity

ALTUNTAŞ DİNLENÇ T., ÖLGEN S.

7th International Symposium on Pharmaceutical Sciences (ISOPS-7), Ankara, Türkiye, 24 - 27 Haziran 2003, (Özet Bildiri)

16. Sulfoxıdatıon of the cysteine and mercapturic acid conjugates derived from the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl) vinyl ether (Compound A)

ALTUNTAŞ DİNLENÇ T., Kharasch E.

7th International Symposium on Pharmaceutical Sciences (ISOPS-7), Ankara, Türkiye, 24 - 27 Haziran 2003, (Özet Bildiri)

17. Role of P-glycoprotein in clinical effects of morphine, fentanyl and methadone.

Kharasch E., Whittington D., ALTUNTAŞ T., Sheffels P., Hoffer C.

Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics, Washington, Kiribati, 2 - 05 Nisan 2003, cilt.73, (Özet Bildiri)

18. Role of P-glycoprotein in the intestinal absorption of morphine, fentanyl and methadone.

Kharasch E., Whittington D., Hoffer C., ALTUNTAŞ T., Sheffels P.

Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics, Washington, Kiribati, 2 - 05 Nisan 2003, cilt.73, (Özet Bildiri)

19. Cytotoxicity of S-conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether in a human proximal tubular cell line (HK-2)

ALTUNTAŞ T., Zager R., Kharasch E.

12th North American ISSX Meeting, PROVIDENCE, RHODE ISLAND, 12 - 16 Ekim 2003, cilt.35, ss.106, (Özet Bildiri)

20. Role of P-glycoprotein in intestinal absorption and clinical effects of morphine, fentanyl and methadone

Kharasch E. D., Whittington D., Hoffer C., ALTUNTAŞ DİNLENÇ T., Sheffels P.

11th International Society for Anesthetic Pharmacology (ISAP), Orlando-Florida, Amerika Birleşik Devletleri, 11 - 14 Ekim 2002, (Özet Bildiri)

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