Doç. Dr. AYŞE SELEN ALP

Yayın Ağı

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Nilotinib exhibits less toxicity than imatinib and influences the immune state by modulating iNOS, p-p38 and p-JNK in LPS/IFN gamma-activated macrophages.

Karabay A. Z., Ozkan T., Koc A., Hekmatshoar Y., Gurkan-Alp A. S., Sunguroglu A.

Toxicology in vitro : an international journal published in association with BIBRA , ss.105754, 2023 (SCI-Expanded)

Some 2-[4-(<i>1H</i>-benzimidazol-1-yl) phenyl]-<i>1H</i>-benzimidazole derivatives overcome imatinib resistance by induction of apoptosis and reduction of P-glycoprotein activity

Hekmatshoar Y., Ozkan T., Alp M., Gurkan-Alp A. S., Sunguroglu A.

CHEMICAL BIOLOGY & DRUG DESIGN , cilt.102, sa.6, ss.1521-1533, 2023 (SCI-Expanded)

Novel indole retinoid derivative induces apoptosis and cell cycle arrest and modulates AKT and ERK signaling in HL-60 cells

Gurkan-Alp A. S., Karabay A. Z., KOÇ A., Buyukbingol E.

FUNDAMENTAL & CLINICAL PHARMACOLOGY , cilt.37, sa.3, ss.557-565, 2023 (SCI-Expanded) Sürdürülebilir Kalkınma

Synthesis of Some Benzimidazole-derived Molecules and their Effects on PARP-1 Activity and MDA-MB-231, MDA-MB-436, MDA-MB-468 Breast Cancer Cell Viability

Gurkan-Alp A. S., Alp M., Karabay A. Z., Koç A., Buyukbingol E.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY , cilt.20, sa.14, ss.1728-1738, 2020 (SCI-Expanded)

Three-Dimensional Analysis of Binding Sites for Predicting Binding Affinities in Drug Design

Erdas-Cicek O., Atac A. O., Gurkan-Alp A. S., Buyukbingol E., ALPASLAN F. N.

JOURNAL OF CHEMICAL INFORMATION AND MODELING , cilt.59, sa.11, ss.4654-4662, 2019 (SCI-Expanded)

Design, synthesis and docking studies of benzimidazole derivatives as potential EGFR inhibitors

ÇELİK İ., KILCIGİL G., GÜVEN B., Kara Z., Gurkan-Alp A. S., KARAYEL A., et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.173, ss.240-249, 2019 (SCI-Expanded)

Apoptotic Effects of Some Tetrahydronaphthalene Derivatives on K562 Human Chronic Myelogenous Leukemia Cell Line

KOÇ A., ÖZKAN T., Hekmatshoar Y., Gurkan-Alp A. S., AKTAN F., Buyukbingol Z., et al.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY , cilt.17, sa.14, ss.1924-1930, 2017 (SCI-Expanded)

Retinoid N-(1H-benzo[d]imidazol-2-yl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamide induces p21-dependent senescence in breast cancer cells

Mumcuoglu M., Gurkan-Alp A. S., Buyukbingol E., Cetin-Atalay R.

STEROIDS , cilt.108, ss.31-38, 2016 (SCI-Expanded)

Synthesis and anticancer effects of some novel 2-(4-phenoxyphenyl)-1H-benzimidazole derivatives on K562 cell line

Gurkan-Alp A. S., GÖKER A. H., ALP M., ÖZKAN T., SUNGUROĞLU A.

ARCHIVES OF PHARMACAL RESEARCH , cilt.38, sa.5, ss.650-658, 2015 (SCI-Expanded)

Inhibitory effects of indole alpha-lipoic acid derivatives on nitric oxide production in LPS/IFN gamma activated RAW 264.7 macrophages

KARABAY A. Z., KOÇ A., Gurkan-Alp A. S., Buyukbingol Z., Buyukbingol E.

CELL BIOCHEMISTRY AND FUNCTION , cilt.33, sa.3, ss.121-127, 2015 (SCI-Expanded)

Synthesis and antiproliferative evaluation of novel 5-(4-methylpiperazin-1-yl)-2-phenyl-1H-benzimidazole derivatives

ALP M., Gurkan-Alp A. S., ÖZKAN T., SUNGUROĞLU A.

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES , cilt.70, sa.3-4, ss.79-85, 2015 (SCI-Expanded)

Synthesis and evaluation of antioxidant activities of novel 1,3,4-oxadiazole and imine containing 1H-benzimidazoles

ALP A. S., KILCIGİL G., ÖZDAMAR E. D., ÇOBAN T., EKE B.

TURKISH JOURNAL OF CHEMISTRY , cilt.39, sa.1, ss.42-53, 2015 (SCI-Expanded)

Compressed images for affinity prediction-2 (CIFAP-2): an improved machine learning methodology on protein-ligand interactions based on a study on caspase 3 inhibitors

Erdas O., Andac C. A., Gurkan-Alp A. S., ALPASLAN F. N., Buyukbingol E.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.30, sa.5, ss.809-815, 2015 (SCI-Expanded)

Synthesis and Biological Evaluation of a Series of Dithiocarbamates as New Cholinesterase Inhibitors

ALTINTOP M. D., Gurkan-Alp A. S., ÖZKAY Y., KAPLANCIKLI Z. A.

ARCHIV DER PHARMAZIE , cilt.346, sa.8, ss.571-576, 2013 (SCI-Expanded)

Aldose Reductase Inhibitory Potential of Several Thiazolyl-thiazolidine-2,4-Diones

Das-Evcimen N., Sarikaya M., Gurkan-Alp A. S., BOZDAĞ DÜNDAR O.

LETTERS IN DRUG DESIGN & DISCOVERY , cilt.10, sa.5, ss.415-419, 2013 (SCI-Expanded)

Compressed images for affinity prediction (CIFAP): a study on predicting binding affinities for checkpoint kinase 1 protein inhibitors

Erdas O., Andac C. A., Gurkan-Alp A. S., ALPASLAN F. N., Buyukbingol E.

JOURNAL OF CHEMOMETRICS , cilt.27, sa.6, ss.155-164, 2013 (SCI-Expanded)

Synthesis, anticancer activities and molecular modeling studies of novel indole retinoid derivatives

Gurkan-Alp A. S., Mumcuoglu M., Andac C. A., Dayanc E., Cetin-Atalay R., Buyukbingol E.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.58, ss.346-354, 2012 (SCI-Expanded)

Synthesis and Evaluation of Antioxidant Properties of Novel 2-[2-(4-chlorophenyl) benzimidazole-1-yl]-N-(2-arylmethylene amino) acetamides and 2-[2-(4-chlorophenyl) benzimidazole-1-yl]-N-(4-oxo-2-aryl-thiazolidine-3-yl) acetamides-I

KILCIGİL G., Gurkan S., ÇOBAN T., ÖZDAMAR E. D., EKE B.

CHEMICAL BIOLOGY & DRUG DESIGN , cilt.79, sa.5, ss.869-877, 2012 (SCI-Expanded)

Synthesis and effects of some novel tetrahydronaphthalene derivatives on proliferation and nitric oxide production in lipopolysaccharide activated Raw 264.7 macrophages

Gurkan A. S., KARABAY A. Z., Buyukbingol Z., Buyukbingol E.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.46, sa.2, ss.468-479, 2011 (SCI-Expanded)

Scavenging of superoxide anion radical and hydroxyl radical by novel thiazolyl-thiazolidine-2,4-dione compounds

BOZDAĞ DÜNDAR O., Gurkan S., Aboul-Enein H. Y., Kruk I., Kladna A.

LUMINESCENCE , cilt.24, sa.3, ss.194-201, 2009 (SCI-Expanded)

Syntheses of novel indole lipoic acid derivatives and their antioxidant effects on lipid peroxidation

Gurkan A. S., Karabay A. Z., Buyukbingol Z., Adejare A., Buyukbingol E.

ARCHIV DER PHARMAZIE , sa.2-3, ss.67-73, 2005 (SCI-Expanded) Sürdürülebilir Kalkınma

Diğer Dergilerde Yayınlanan Makaleler

Tirozin Kinaz Enzim İnhibitörü Yeni Bileşikler ve Yapı-Aktivite İlişkilerinin Değerlendirilmesi

Gurkan-Alp A. S., Bozca F.

FABAD JOURNAL OF PHARMACEUTICAL SCIENCES , cilt.44, sa.1, ss.65-78, 2019 (Scopus)

Bazi Retinoidal Bileşiklerin RXRa Proteinine Doking Çalışmaları

Gurkan-Alp A. S., Büyükbingöl M. E.

Ankara Ecz. Fak. Derg. , cilt.38, sa.3, ss.155-166, 2009 (Scopus)

Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar

Synthesis of Some Novel N'-((Aryl)Methylene)-1H-Indole-5-Carbohydrazides

Gurkan-Alp A. S., Avuka Ö. F.

International Symposium on Pharmaceutical Sciences (ISOPS-13), Ankara, Türkiye, 22 - 25 Haziran 2021, ss.197-198

Synthesis of Some Novel Schiff Bases Incorporated with Indazole Moiety

Kayıkçı-Paşa N., Gurkan-Alp A. S.

International Symposium on Pharmaceutical Sciences (ISOPS-13), Ankara, Türkiye, 22 - 25 Haziran 2021, ss.197

Synthesis of Some Novel 4-(1H-Benzimidazol-1-yl)-N'-Benzylidenebenzohydrazide Derivatives

Alp M., Gurkan-Alp A. S.

International Symposium on Pharmaceutical Sciences (ISOPS-13), Ankara, Türkiye, 22 - 25 Haziran 2021, ss.190-191

Synthesis and Anticancer Activity Studies of Some Novel Indole Retinoid Derivatives

Gurkan-Alp A. S., Koç A., Karabay A. Z., Büyükbingöl M. E.

International Symposium on Pharmaceutical Sciences (ISOPS-12), Ankara, Türkiye, 26 - 29 Haziran 2018, ss.399

Molecular Docking Studies of Some Novel Benzimidazole Derivatives as EGFR Inhibitors

Gurkan-Alp A. S., Çelik İ., Kılcıgil G.

International Symposium on Pharmaceutical Sciences (ISOPS-12), Ankara, Türkiye, 26 - 29 Haziran 2018, ss.400

Synthesis and anticancer effects of some novel benzimidazole-derived PARP inhibitor molecules

Alp M., Gurkan-Alp A. S., Karabay A. Z., Büyükbingöl M. E.

2nd International Gazi Pharma Symposium Series (GPSS-2017), Ankara, Türkiye, 11 - 13 Ekim 2017

Effect of retinoid derivates on cholinesterase activity

Gök M., Gurkan-Alp A. S., Büyükbingöl M. E., Bodur E.

42nd FEBS Congress, Yerushalayim, İsrail, 10 - 14 Eylül 2017, cilt.284, ss.327

Retinoid analoglarının kronik miyeloid lösemi k562 hücrelerindeki apoptotik etkileri

Koç A., Karabay A. Z., Özkan T., Gurkan-Alp A. S., Aktan F., Büyükbingöl Z., et al.

23. Ulusal Biyoloji Kongresi, Gaziantep, Türkiye, 5 - 09 Eylül 2016, ss.183

Effects of indole alpha lipoic acid derivatives on cell viability parameters in K562 leukemia cell line

Karabay A. Z., Koç A., Gurkan-Alp A. S., Büyükbingöl Z., Büyükbingöl M. E.

11th International Symposium on Pharmaceutical Sciences (ISOPS-11), Ankara, Türkiye, 9 - 12 Haziran 2015, ss.43

Mdm2 P53 Etkileşimini İnhibe Edecek Antikanser Etkili Yeni Spiro Oksiindol Türevleri

Andaç A. C., Konyar D., Gurkan-Alp A. S., Noyanalpan N., Büyükbingöl M. E.

27. Ulusal Kimya Kongresi, Çanakkale, Türkiye, 23 - 28 Ağustos 2015, ss.499

Anticancer evaluation of Some 5-(4-Methylpiperazin-1-yl)-2-Phenyl-1H-Benzimidazole Derivatives

Alp M., Gurkan-Alp A. S., Özkan T., Sunguroğlu A.

11th International Symposium on Pharmaceutical Sciences (ISOPS-11), Ankara, Türkiye, 9 - 12 Haziran 2015, ss.289

Effects of indole α-lipoic acid derivatives on nitric oxide production in LPS/IFN-γ activated RAW 264.7 macrophages.

Karabay A. Z., Koç A., Gurkan A. S., Büyükbingöl Z., Büyükbingöl M. E.

FES/EMBO, Paris, Fransa, 30 Ağustos - 04 Eylül 2014, ss.281

Synthesis and evaluation of antioxidant activities of novel 1,3,4-oxadiazole and imine containing 1H-benzimidazoles

Gurkan-Alp A. S., Kılcıgil G., Özdamar E. D., Çoban T., Eke B.

20th International Conference on Organic Synthesis (ICOS-20), Budapest, Macaristan, 29 Haziran - 04 Temmuz 2014, ss.1

Compressed Images for Affinity Prediction (CIFAP): A Novel Machine Learning Methodology on Protein-Ligand Interactions

Erdaş Ö., Andac C. A., Gurkan-Alp A. S., Alpaslan F. N., Buyukbıngol E.

2nd International BAU-Drug Design Symposium, İstanbul, Türkiye, 17 - 19 Nisan 2014, ss.31

Compressed Images for Affinity Prediction (CIFAP): A Novel Machine Learning Methodology on Protein-Ligand Interactions

Buyukbingol E., Erdaş Ö., Andac C. A., Gurkan-Alp A. S., Alpaslan F. N.

International Conference on Omics Studies, Florida, Amerika Birleşik Devletleri, 4 - 05 Eylül 2013, cilt.6, ss.48

Synthesis of some novel N-substituted 4-trans,trans-farnesylthiobenzamide derivatives as potential anticancer agents

Demirci A., Gurkan-Alp A. S., Buyukbingol E.

13th Belgian Organic Synthesis Symposium (BOSS XIII), Leuven, Belçika, 15 - 20 Temmuz 2012, ss.162

Synthesis and evaluation of antioxidant activities of novel 2-(substitutedbenzylthio)-5-((2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)methyl)-1,3,4-oxadiazoles

Gurkan-Alp A. S., Kılcıgil G., Özdamar E. D., Çoban T., Eke B.

10th International Symposium on Pharmaceutical Sciences (ISOPS-10), Ankara, Türkiye, 26 - 29 Haziran 2012, ss.162

Predicting binding affinities of drug-protein interactions by analysis of binding site images

Erdaş Ö., Andac C. A., Gurkan-Alp A. S., Alpaslan F. N., Buyukbingol E.

10th International Symposium on Pharmaceutical Sciences (ISOPS-10), Ankara, Türkiye, 26 - 29 Haziran 2012, ss.50

Synthesis of some novel N-substituted 3-trans,trans-farnesylthiobenzamide derivatives as potential anticancer agents

Demirci A., Gurkan-Alp A. S., Buyukbingol E.

10th International Symposium on Pharmaceutical Sciences (ISOPS-10), Ankara, Türkiye, 26 - 29 Haziran 2012, ss.161

Synthesis of some novel N-substituted farnesylthiosalicylamide derivatives

Elmazoğlu Z., Gurkan-Alp A. S., Buyukbingol E.

4th European Conference on Chemistry for Life Sciences (4ECCLS), Budapest, Macaristan, 31 Ağustos - 03 Eylül 2011, ss.192

Novel retinoid derivatives against breast cancer

Mumcuoğlu M., Gurkan-Alp A. S., Atalay R., Buyukbingol E.

4th International Symposium on Advances in Synthetic and Medicinal Chemistry (ASMC11), Sankt-Peterburg, Rusya, 21 - 25 Ağustos 2011, ss.205

Synthesis of some novel indole retinoid derivatives as potential antitumor agents

Gurkan A. S., Buyukbingol E.

18th International Conference on Organic Synthesis (ICOS-18) - Medicinal Chemistry and Agrochemicals, Bergen, Norveç, 1 - 06 Ağustos 2010, ss.343

Yeni Retinoid Bileşiklerinin Tasarlanması, Sentezi, Yapı Aydınlatılması, Biyolojik Etki Tayini ve Yapı-Aktivite Çalışmaları

Gurkan A. S., Buyukbingol E.

2. Ulusal Farmasötik Kimya Kongresi, Mersin, Türkiye, 13 - 15 Kasım 2009, ss.9

Synthesis and Evaluation of Antioxidant Properties of Some 2-[2-(4-chlorophenyl)benzimidazol-1-yl]-N-(4-oxo-2-substitutedphenyl-thiazolidin-3-yl)acetamides

Kılcıgil G., Gurkan A. S., Çoban T., Özdamar E. D., Eke B.

3rd European Conference on Chemistry for Life Sciences: Linking Chemistry with Biological Activity, Frankfurt, Almanya, 2 - 05 Eylül 2009, ss.176

Effects of some novel tetrahydronaphthalene derivatives on proliferation and nitric oxide production in lipopolysaccharide activated RAW 264.7 macrophages

Gurkan A. S., Karabay A. Z., Büyükbingöl Z., Büyükbingöl M. E.

9th International Symposium on Pharmaceutical Sciences, Ankara, Türkiye, 23 - 26 Haziran 2009, ss.239

Synthesis and Structural Elucidation of Some Novel Tetrahydronaphthalene Derivatives as Retinoid Analogues

Gurkan A. S., Alagöz Z., Buyukbingol E.

International Conference on Medicinal Chemistry (RICT-45), Orleans, Fransa, 1 - 03 Temmuz 2009, ss.131

Synthesis and Antidiabetic Activity of Some New Thiazolyl Thiazolidine-2,4-Dione Derivatives

Bozdağ Dündar O., Gurkan A. S., Verspohl E. J., Hüppe E., König M.

International Conference on Medicinal Chemistry (RICT-45), Orleans, Fransa, 1 - 03 Temmuz 2009, ss.114

Synthesis and Structural Elucidation by Electron Paramagnetic Resonance (EPR) Spectroscopy of a Novel Retinoidal Nitroxide Derivative: 5,5,8,8-Tetramethyl-N-(2,2,6,6-tetramethylpiperidine-1-oxyl-4-yl)-5,6,7,8-tetrahydronaphthalene-2-carboxamide

Gurkan A. S., Yonar D., Buyukbingol E.

9th International Symposium on Pharmaceutical Sciences (ISOPS-9), Ankara, Türkiye, 23 - 26 Haziran 2009, ss.238

Syntheses and Antioxidant Effects on Lipid Peroxidation of Novel Indole Lipoic Acid Derivatives

Gurkan A. S., Karabay A. Z., Buyukbingol Z., Adejare A., Buyukbingol E.

20th International Congress of Heterocyclic Chemistry (20th-ICHC), Palermo, İtalya, 31 Temmuz - 05 Ağustos 2005, ss.362

Metrikler

Yayın

Atıf (WoS)

222

H-İndeks (WoS)

Atıf (Scopus)

354

H-İndeks (Scopus)

Proje

Tez Danışmanlığı

Açık Erişim

BM Sürdürülebilir Kalkınma Amaçları

Yayınlar & Eserler