Apoptotic Effects of Some Tetrahydronaphthalene Derivatives on K562 Human Chronic Myelogenous Leukemia Cell Line

KOÇ A., ÖZKAN T., Hekmatshoar Y., Gurkan-Alp A. S., AKTAN F., Buyukbingol Z., ...Daha Fazla

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.17, sa.14, ss.1924-1930, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 14
  • Basım Tarihi: 2017
  • Doi Numarası: 10.2174/1871521409666170412122811
  • Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1924-1930
  • Anahtar Kelimeler: Retinoids, chronic myelogenous leukemia, apoptosis, cancer, K562, tetrahydronaphthalene, CHRONIC MYELOID-LEUKEMIA, TRANS-RETINOIC ACID, BREAST-CANCER CELLS, SUCCINATE-INDUCED APOPTOSIS, TYROSINE KINASE INHIBITORS, FERULIC ACID, DEATH, PROLIFERATION, RESISTANCE, THERAPY
  • Ankara Üniversitesi Adresli: Evet

Özet

Background: Retinoids which are vitamin A (Retinol) derivatives have been suggested to mediate the inhibition of cancer cell growth and apoptosis. It has been reported that all trans retinoic acid (ATRA) exhibited suppressive effects on different types of leukemia including chronic myelogenous leukemia.