Prof. PELİN MUTLU

Publication Network

Articles 36

1. Design, Synthesis, Molecular Docking, Dynamics Simulation, and Biological Evaluation of Novel Thiazolidinedione Derivatives Against Breast Cancer with Apoptosis-Inducing Activity

Zarrin P., Gado S., Farhang Boroujeni A., Gadasli I., BOZKURT F. Z., CANSARAN DUMAN D., et al.

ACS OMEGA , 2025 (SCI-Expanded, Scopus)

2. Nanostructured 316L Stainless Steel Stent Surfaces Improve Corrosion Resistance, and Enhance Endothelization and Hemocompatibility

Erdogan Y. K., MUTLU P., ERCAN B.

Advanced Materials Interfaces , vol.12, no.14, 2025 (SCI-Expanded, Scopus)

3. Differential synergistic effects of palbociclib and doxorubicin on doxorubicin-resistant cancer cells with diverse tumor origins

Yalcin G. D., MUTLU P., Kazan H. H., GÜNDÜZ U.

JOURNAL OF CHEMOTHERAPY , vol.37, no.3, pp.247-255, 2025 (SCI-Expanded, Scopus)

4. Application of Inorganic Nanomaterials in Transdermal and Topical Medications: Influential Parameters, Opportunities and Challenges

Servatan M., MUTLU P., ERTUNÇ S., Sanaeifard S., Sahin B., YILMAZER HİTİT Z.

COMMENTS ON INORGANIC CHEMISTRY , vol.45, no.2, pp.88-135, 2025 (SCI-Expanded, Scopus)

5. **Synthesis, Anticancer Activity, and In Silico Modeling of Alkylsulfonyl Benzimidazole Derivatives: Unveiling Potent Bcl-2 Inhibitors for Breast Cancer**

Abbade Y., KIŞLA M. M., Hassan M. A., ÇELİK İ., Dogan T. S., MUTLU P., et al.

ACS OMEGA , vol.9, no.8, pp.9547-9563, 2024 (SCI-Expanded, Scopus)

6. Drug metabolism and inflammation related distinct miRNA signature of colchicine resistant familial Mediterranean fever patients

Tümerdem B. Ş., AKBABA T. H., BATU AKAL E. D., AKKAYA ULUM Z. Y., MUTLU P., ÖZEN S., et al.

International Immunopharmacology , vol.124, 2023 (SCI-Expanded, Scopus)

7. Investigation of the Therapeutic Effects of Palbociclib Conjugated Magnetic Nanoparticles on Different Types of Breast Cancer Cell Lines

Parsian M., MUTLU P., Taghavi Pourianazar N., Yalcin Azarkan S., Gunduz U.

Cellular and Molecular Bioengineering , vol.16, no.2, pp.143-157, 2023 (SCI-Expanded, Scopus)

8. Identification of Single-nucleotide Alterations in MAP3K8 Gene in a Turkish Head and Neck Squamous Cell Carcinoma Patient Group

MUTLU P., Mutlu M., Yalçin-Azarkan S., Bayir Ö., Saylam G., Korkmaz M. H.

Turk Onkoloji Dergisi , vol.38, no.3, pp.257-263, 2023 (ESCI, Scopus, TRDizin)

9. Vancomycin Containing PDLLA and PLGA/beta-TCP Inhibit Biofilm Formation but Do Not Stimulate Osteogenic Transformation of Human Mesenchymal Stem Cells

Kankilic B., Bayramli E., KORKUSUZ P., EROĞLU H., ŞENER B., Mutlu P., et al.

FRONTIERS IN SURGERY , vol.9, 2022 (SCI-Expanded, Scopus)

10. Development of a microfluidic platform to maintain viability of micro-dissected tumor slices in culture

Parsian M., Mutlu P., YILDIRIM E., Ildiz C., Ozen C., Gunduz U.

BIOMICROFLUIDICS , vol.16, no.3, 2022 (SCI-Expanded, Scopus)

11. NEK6 gene silencing using siRNA for overcome multidrug resistance in chronic myeloid leukemia cells

Nabioğlu A., MUTLU P., YALÇIN AZARKAN S., GÜNDÜZ U.

Avrasya Arastirma Gelistirme Bilim ve Teknoloji Merkezi Limited Sirketi , 2022 (Peer-Reviewed Journal)

12. Identification of Mitochondrial DNA Gene Mutations in a Turkish Head and Neck Squamous Cancer Patient Group

MUTLU P., Mutlu M., YALÇIN AZARKAN S., Keseroglu K., Bayir O., Saylam G., et al.

UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI , vol.32, no.2, pp.109-118, 2022 (SCI-Expanded, Scopus)

13. EVALUATION OF METHYLATION PROFILES OF AN EPIDERMAL GROWTH FACTOR RECEPTOR GENE IN A HEAD AND NECK SQUAMOUS CELL CARCINOMA PATIENT GROUP

Mutlu M., Mutlu P., Azarkan S., Bayir O., Ocal B., Saylam G., et al.

BALKAN JOURNAL OF MEDICAL GENETICS , vol.23, no.2, pp.65-72, 2020 (SCI-Expanded, Scopus)

14. Characterization of Gemcitabine Loaded Polyhydroxybutyrate Coated Magnetic Nanoparticles for Targeted Drug Delivery

Parsian M., Mutlu P., Yalcin S., Gunduz U.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY , vol.20, no.10, pp.1233-1240, 2020 (SCI-Expanded, Scopus)

15. Co-delivery of Doxorubicin and D-alpha-Tocopherol Polyethylene Glycol 1000 Succinate by Magnetic Nanoparticles

Metin E., Mutlu P., Gunduz U.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY , vol.18, no.8, pp.1138-1147, 2018 (SCI-Expanded, Scopus)

16. DETERMINATION OF THE RELATIONSHIP BETWEEN DOXORUBICIN RESISTANCE AND WNT SIGNALING PATHWAY IN HELA AND K562 CELL LINES

Mutlu P., Azarkan S. Y., Pourianazar N. T., Yucel M., Gunduz U.

EXCLI JOURNAL , vol.17, pp.386-398, 2018 (SCI-Expanded, Scopus)

17. Half generations magnetic PAMAM dendrimers as an effective system for targeted gemcitabine delivery

Parsian M., Mutlu P., Yalcin S., TEZCANER A., Gunduz U.

INTERNATIONAL JOURNAL OF PHARMACEUTICS , vol.515, no.1-2, pp.104-113, 2016 (SCI-Expanded, Scopus)

18. Loading of Gemcitabine on chitosan magnetic nanoparticles increases the anti-cancer efficacy of the drug

Parsian M., Unsoy G., Mutlu P., Yalcin S., TEZCANER A., Gunduz U.

EUROPEAN JOURNAL OF PHARMACOLOGY , vol.784, pp.121-128, 2016 (SCI-Expanded, Scopus)

19. An update on molecular biology and drug resistance mechanisms of multiple myeloma

Mutlu P., Kiraz Y., Gunduz U., Baran Y.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY , vol.96, no.3, pp.413-424, 2015 (SCI-Expanded, Scopus)

20. Association between XRCC3 Thr241Met polymorphism and laryngeal cancer susceptibility in Turkish population

Mutlu P., Mutlu M., Yalcin S., YAYLACI A., Unsoy G., Saylam G., et al.

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY , vol.272, no.12, pp.3779-3784, 2015 (SCI-Expanded, Scopus)

21. Identification of XRCC1 Arg399Gln and XRCC3 Thr241Met Polymorphisms in a Turkish Population and Their Association with the Risk of Chronic Lymphocytic Leukemia

Mutlu P., Elci M. P., Yildirim M., Nevruz O., Cetin A. T., Avcu F.

INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION , vol.31, no.3, pp.332-338, 2015 (SCI-Expanded, Scopus)

22. Detection of XRCC1 gene polymorphisms in Turkish head and neck squamous cell carcinoma patients: a comparative analysis with different populations

Mutlu P., Mutlu M., Yalcin S., Unsoy G., YAYLACI A., Saylam G., et al.

JOURNAL OF BUON , vol.20, no.2, pp.540-547, 2015 (SCI-Expanded, Scopus)

23. The-137G/C Polymorphism in Interleukin-18 Gene Promoter Contributes to Chronic Lymphocytic and Chronic Myelogenous Leukemia Risk in Turkish Patients

Yalcin S., Mutlu P., Cetin T., Sarper M., Ozgur G., Avcu F.

TURKISH JOURNAL OF HEMATOLOGY , vol.32, no.4, pp.311-316, 2015 (SCI-Expanded, Scopus, TRDizin)

24. Polyhydroxybutyrate-Coated Magnetic Nanoparticles for Doxorubicin Delivery: Cytotoxic Effect Against Doxorubicin-Resistant Breast Cancer Cell Line

Yalcin S., Unsoy G., Mutlu P., Khodadust R., Gunduz U.

AMERICAN JOURNAL OF THERAPEUTICS , vol.21, no.6, pp.453-461, 2014 (SCI-Expanded, Scopus)

25. Synthesis of Doxorubicin loaded magnetic chitosan nanoparticles for pH responsive targeted drug delivery

Unsoy G., Khodadust R., Yalcin S., Mutlu P., Gunduz U.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES , vol.62, pp.243-250, 2014 (SCI-Expanded, Scopus)

26. Different Types of Cell Cycle- and Apoptosis-Related Gene Expressions Alter in Corticosteroid-, Vincristine-, and Melphalan-Resistant U-266 Multiple Myeloma Cell Lines

Mutlu P., Ural A. U., Gunduz U.

TURKISH JOURNAL OF HEMATOLOGY , vol.31, no.3, pp.231-238, 2014 (SCI-Expanded, Scopus, TRDizin)

27. Idarubicin-loaded folic acid conjugated magnetic nanoparticles as a targetable drug delivery system for breast cancer

Gunduz U., Keskin T., Tansik G., Mutlu P., Yalcin S., Unsoy G., et al.

BIOMEDICINE & PHARMACOTHERAPY , vol.68, no.6, pp.729-736, 2014 (SCI-Expanded, Scopus)

28. Association of -174G/C interleukin-6 gene polymorphism with the risk of chronic lymphocytic, chronic myelogenous and acute myelogenous leukemias in Turkish patients

MUTLU P., Yalcin S., Elei P., Yildirim M., Cetin A. T., Avcu F.

Journal of B.U.ON. , vol.19, no.3, pp.787-791, 2014 (SCI-Expanded, Scopus)

29. Chitosan magnetic nanoparticles for pH responsive Bortezomib release in cancer therapy

Unsoy G., Yalcin S., Khodadust R., Mutlu P., Onguru O., Gunduz U.

BIOMEDICINE & PHARMACOTHERAPY , vol.68, no.5, pp.641-648, 2014 (SCI-Expanded, Scopus)

30. Bioapplications of poly(amidoamine) (PAMAM) dendrimers in nanomedicine

Pourianazar N. T., Mutlu P., Gunduz U.

JOURNAL OF NANOPARTICLE RESEARCH , vol.16, no.4, 2014 (SCI-Expanded, Scopus)

31. Polyinosinic: polycytidylic acid loading onto different generations of PAMAM dendrimer-coated magnetic nanoparticles

Khodadust R., Mutlu P., Yalcin S., Unsoy G., Gunduz U.

JOURNAL OF NANOPARTICLE RESEARCH , vol.15, no.8, 2013 (SCI-Expanded, Scopus)

32. Differential oncogene-related gene expressions in myeloma cells resistant to prednisone and vincristine

Mutlu P., Ural A. U., Gunduz U.

BIOMEDICINE & PHARMACOTHERAPY , vol.66, no.7, pp.506-511, 2012 (SCI-Expanded, Scopus)

33. Differential gene expression analysis related to extracellular matrix components in drug-resistant RPMI-8226 cell line

Mutlu P., Ural A. U., Gunduz U.

BIOMEDICINE & PHARMACOTHERAPY , vol.66, no.3, pp.228-231, 2012 (SCI-Expanded, Scopus)

34. Effect of cobalt-60 (gamma radiation) on multidrug-resistant multiple myeloma cell lines

Mutlu P., Baran Y., Ural A. U., Avcu F., Dirican B., Beyzadeoglu M., et al.

CELL BIOLOGY INTERNATIONAL , vol.35, no.7, pp.721-725, 2011 (SCI-Expanded, Scopus)

35. Expression of Multidrug Resistance 1, Lung Resistance Protein and Breast Cancer Resistance Protein Genes in Chronic Leukemias

Iseri O. D., Kars M. D., Mutlu P., Avcu F., Ural A. U., Gunduz U.

UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI , vol.21, no.2, pp.92-100, 2011 (SCI-Expanded, Scopus, TRDizin)

36. Multidrug Resistance Mediated by MRP1 Gene Overexpression in Breast Cancer Patients

Abaan O. D., Mutlu P., Baran Y., Atalay C., Gunduz U.

CANCER INVESTIGATION , vol.27, no.2, pp.201-205, 2009 (SCI-Expanded, Scopus)

Papers Presented at Peer-Reviewed Scientific Conferences 11

1. The new drug candidate molecule evernic acid shows therapeutic activity through the apoptosis pathway by regulating gene and protein expression levels in ovarian cancer cells

Parıltı D. N., Ensoy M., Kaplan İlhan K. N., MUTLU P., GÜR DEDEOĞLU B., CANSARAN DUMAN D.

7th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2024), 02 October 2024, (Summary Text)

2. Synthesis and Investigation of Anti-Cancer Activity of Novel Substituted Alkylsulfonyl 1H-benzo[d]imidazole Derivatives in MCF-7 Breast Cancer Cells

Abbade Y., KIŞLA M. M., Hasan M. A., Somay Doğan T., KAŞKATEPE B., MUTLU P., et al.

5th International Eurasian Conference on Biological and Chemical Sciences, Turkey, 23 November 2022, (Summary Text)

3. AML Genetiği

MUTLU P.

VIII. Uluslararası Katılımlı Deneysel Hematoloji Kongresi, Turkey, 09 September 2022, (Summary Text)

4. Cytotoxic Effect of Palbociclib Conjugated PAMAM Dendrimer Coated Magnetic Nanoparticles on Different Types of Breast Cancer Cell Lines

Parsian M., MUTLU P., TAGHAVI POURIANAZAR N., YALÇIN AZARKAN S., GÜNDÜZ U.

NANOTR-16 (16th Nanoscience and Nanotechnology Conference), Turkey, 05 September 2022, (Summary Text)

5. Development of a microfluidic platform to maintain viability of micro-dissected tumor slices in culture

Parsian M., MUTLU P., YILDIRIM E., Ildız C., ÖZEN C., GÜNDÜZ U.

The Sixth International Symposium on Pharmaceutical and Biomedical Sciences (ISPBS-6, Turkey, 26 - 28 May 2022, (Summary Text)

6. Türk HNSCC hasta grubunda MAP3K8 genindeki tek nükleotid değişikliklerinin belirlenmesi

MUTLU P., MUTLU M., YALÇIN AZARKAN S., KESEROĞLU K., BAYIR Ö., SAYLAM G., et al.

16.Türk Rinoloji Kongresi, 4.Ulusal Baş Boyun Cerrahisi Kongresi ve 1. Çocuk Kulak Burun Boğaz ve Baş Boyun Cerrahisi Kongresi, Ankara, Turkey, 12 May 2022, (Summary Text)

7. Targeting ability and internalization of gemcitabine loaded polyhydroxybutyrate coated magnetic nanoparticles on breast cáncer cell lines.

Parsian M., MUTLU P., YALÇIN AZARKAN S., Gündüz U.

Uluslararası katılımlı 7. Multidisipliner Kanser Araştırma 1. Temel Onkoloji Kongresi, Turkey, 11 - 14 October 2018, (Summary Text)

8. Polyhydroxybutyrate (Phb) Coated Magnetic Nanoparticles For Targeting Delivery of Gemcitabine.

Parsian M., MUTLU P., YALÇIN AZARKAN S., Gündüz U.

International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2018), 26 - 27 April 2018, (Summary Text)

9. Gene expression analysis related to drug resistance and wnt signaling pathway in doxorubicin resistant K562 cell line.

MUTLU P., YALÇIN AZARKAN S., Taghavi Pourianazar N., Meral Y., GÜNDÜZ U.

XV. Ulausal Tıbbi Biyoloji ve Genetik Kongresi, Turkey, 26 - 28 October 2017, (Summary Text)

10. the-137G/C Polymorphism in Interleukin-18 Gene Promoter Contributes to Chronic Myeloid Leukemia Risk in Turkish Patients

Yalcin S., Mutlu P., Cetin T., Sarper M., Ozgur G., Avcu F.

56th Annual Meeting of the American-Society-of-Hematology, San-Francisco, Costa Rica, 6 - 09 December 2014, vol.124, (Summary Text)

11. Conjugation of gemcitabine to PAMAM dendrimer-coated magnetic nanoparticles for targeted delivery

Parsian M., PourianAzar N. T., Yalcin S., Mutlu P., Gunduz U.

FEBS EMBO 2014 Conference, Paris, France, 30 August - 04 September 2014, vol.281, pp.449-450, (Summary Text)

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