Co-delivery of Doxorubicin and D-alpha-Tocopherol Polyethylene Glycol 1000 Succinate by Magnetic Nanoparticles


Metin E., Mutlu P., Gunduz U.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.18, sa.8, ss.1138-1147, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 8
  • Basım Tarihi: 2018
  • Doi Numarası: 10.2174/1871520618666180313154724
  • Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1138-1147
  • Anahtar Kelimeler: Breast cancer, doxorubicin, MNP, targeted co-delivery, vitamin E TPGS, PLGA, VITAMIN-E TPGS, DRUG-DELIVERY, PLGA NANOPARTICLES, IN-VITRO, CANCER, CHEMOTHERAPY, OPTIMIZATION, RESISTANCE, THERAPIES, DOCETAXEL
  • Ankara Üniversitesi Adresli: Hayır

Özet

Background: Although conventional chemotherapy is the most common method for cancer treatment, it has several side effects such as neuropathy, alopecia and cardiotoxicity. Since the drugs are given to body systemically, normal cells are also affected, just like cancer cells. However, in recent years, targeted drug delivery has been developed to overcome these drawbacks.