Education
2021 - 2022
2021 - 2022Post Doctorate
University of Alberta, Faculty of Medicine, Pediatrics, Canada
2014 - 2019
2014 - 2019Doctorate
Ankara University, Sağlık Bilimleri Enstitüsü, Farmakoloji (Dr) (Eczacılık), Turkey
2008 - 2013
2008 - 2013Undergraduate
Gazi University, Eczacılık Fakültesi, Eczacılık Pr., Turkey
Research Areas
Pharmacology and Therapeutics
Professional Sciences
Pharmacology
Health Sciences
Academic Positions
2014 - Continues
2014 - ContinuesAssistant Professor
Ankara University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
Articles
All (14)
SCI-E, SSCI, AHCI (11)
SCI-E, SSCI, AHCI, ESCI (13)
ESCI (2)
Scopus (13)
TRDizin (2)
2025
20251. Optimization of Semi-Solid Lipid Nanoparticle Dispersions by Quality by Design Approach for Dermal Delivery of Curcumin
BADILLI F. U., Sen A., Yegen G., GÜVEN ÇİLOĞLU B., Aksu B., Onay Besikci A.
Journal of Cluster Science
, vol.36, no.5, 2025 (SCI-Expanded)
2025
20252. Effects of EDTA, fumaric acid, and the chitosan solutions prepared with distilled water and acetic acid on dentin microhardness and tubular penetration: An in vitro study.
Sariçam E., Altınışık H., Bulak N., Güven B., Yurdagül S. Z., Amasya G.
Dental and medical problems
, 2025 (ESCI)
2024
20243. The Impact of Levothyroxine and Testosterone Administration on Bladder Contractility in the Rat Model of Propylthiouracil-Induced Hypothyroidism
YILMAZ ORAL D., GÜVEN ÇİLOĞLU B., GÜR S.
UROLOGY RESEARCH AND PRACTICE , 2024 (Peer-Reviewed Journal)
2024
20244. Mitochondrial fatty acid oxidation is the major source of cardiac ATP production in heart failure with preserved ejection fraction.
Sun Q., Güven B., Wagg C. S., de Oliveira A. A., Silver H., Zhang L., et al.
Cardiovascular research
, 2024 (SCI-Expanded)
2024
20245. Obesity Is a Major Determinant of Impaired Cardiac Energy Metabolism in Heart Failure with Preserved Ejection Fraction.
Güven B., Sun Q., Wagg C. S., Almeida de Oliveira A., Silver H., Persad K. L., et al.
The Journal of pharmacology and experimental therapeutics
, vol.388, no.1, pp.145-155, 2024 (SCI-Expanded)
2023
20236. Stimulating cardiac glucose oxidation lessens the severity of heart failure in aged female mice.
Sun Q., Wagg C. S., Güven B., Wei K., de Oliveira A. A., Silver H., et al.
Basic research in cardiology
, 2023 (SCI-Expanded)
2023
20237. Past and present of beta arrestins: A new perspective on insulin secretion and effect.
GÜVEN B., Onay-Besikci A.
European journal of pharmacology
, vol.956, pp.175952, 2023 (SCI-Expanded)
2023
20238. Combined levothyroxine and testosterone treatment for restoring erectile dysfunction in propylthiouracil-induced hypothyroid rats
Korkmaz F. N., Yilmaz-Oral D., Asker H., Guven B., Turkcan D., Kirlangic Ö. F., et al.
JOURNAL OF SEXUAL MEDICINE
, vol.20, no.6, pp.732-741, 2023 (SCI-Expanded)
2023
20239. In Vitro and in Silico Evaluation of Some New 1H-Benzimidazoles Bearing Thiosemicarbazide and Triazole as Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
ÇELİK İ., Ayhan-Kilcigil G., GÜVEN B., Kara Z., Onay-Besikci A.
POLYCYCLIC AROMATIC COMPOUNDS
, vol.43, no.1, pp.444-455, 2023 (SCI-Expanded)
2022
202210. Pleiotropic vascular effects of ivabradine in streptozotocin-induced diabetes
Kara Z., GÜVEN B., BEŞİKCİ A., YILDIRIM N., ALTUNAY H.
EUROPEAN JOURNAL OF PHARMACOLOGY
, vol.916, 2022 (SCI-Expanded)
2022
202211. Synthesis, molecular docking, in silico ADME, and EGFR kinase inhibitor activity studies of some new benzimidazole derivatives bearing thiosemicarbazide, triazole, and thiadiazole
ÇELİK İ., Ayhan-Kilcigil G., Karayel A., GÜVEN B., BEŞİKCİ A.
JOURNAL OF HETEROCYCLIC CHEMISTRY
, vol.59, no.2, pp.371-387, 2022 (SCI-Expanded)
2020
202012. Metabolic effects of carvedilol through beta-arrestin proteins: investigations in a streptozotocin-induced diabetes rat model and in C2C12 myoblasts
GÜVEN B., Kara Z., BEŞİKCİ A.
BRITISH JOURNAL OF PHARMACOLOGY
, vol.177, no.24, pp.5580-5594, 2020 (SCI-Expanded)
2019
201913. Design, synthesis and docking studies of benzimidazole derivatives as potential EGFR inhibitors
ÇELİK İ., KILCIGİL G., GÜVEN B., Kara Z., Gurkan-Alp A. S., KARAYEL A., et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, vol.173, pp.240-249, 2019 (SCI-Expanded)
2017
201714. Synthesis and Pharmacologic Evaluation of Some Benzimidazole Acetohydrazide Derivatives as EGFR Inhibitors
Demirel S., KILCIGİL G., Kara Z., GÜVEN B., BEŞİKCİ A.
TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
, vol.14, no.3, pp.285-289, 2017 (ESCI)
Papers Presented at Peer-Reviewed Scientific Conferences
2023
20231. Chronic Effects of Carvedilol on Erectile Dysfunction in STZ-Induced Diabetic Rats
GÜVEN ÇİLOĞLU B., YILMAZ ORAL D., KARA Z., GÜR S., BEŞİKCİ A.
14. Uluslararası Tıp ve Sağlık Bilimleri Araştırmaları Kongresi- UTSAK, Ankara, Turkey, 23 - 24 December 2023, (Summary Text)
2022
20222. The Warburg effect is reduced in matured cardiomyocytes due primarily to a decrease in glycolysis
PERSAD K. L., ANDRE D. J., GÜVEN ÇİLOĞLU B., HOUNCAREN M., ZHANG L., GREENWOOD J., et al.
ISHR 2022, Winnipeg, Canada, 6 - 09 September 2022, (Summary Text)
2022
20223. Ketones promote maturation of proliferating H9c2 cardiomyocytes.
PERSAD K. L., GÜVEN B., HOUNCAREN M., LOPASCHUK G.
Society of Heart and Vascular Metabolism, Seoul, South Korea, 16 October 2022, (Summary Text)
2022
20224. Cardiac glucose oxidation is suppressed in heart failure with preserved ejection fraction
SUN Q., GÜVEN B., WAGG C., OLIVEIRA A. A., SILVER H., ZHANG L., et al.
Society for Heart and Vascular Metabolism, Seoul, South Korea, 16 - 19 October 2022, (Summary Text)
2022
20225. Metabolic Effects of Carvedilol on Control and HFpEF Mouse Heart and Hypertrophied H9c2 Cells: The Potential Contribution of a Biased Agonist Effect
GÜVEN B., QIUYU S., PERSAD K. L., WAGG C., OLIVEIRA A. A., SILVER H., et al.
ECCR 2022, Treviso, Italy, 30 September - 02 October 2022, (Summary Text)
2022
20226. Cardiac glucose oxidation is impaired in heart failure with preserved ejection fraction (HFpEF).
Sun Q., Güven B., Wagg C., Olıveıra A. A., Sılver H., Arana A., et al.
ISHR 2022, Winnipeg, Canada, 06 September 2022, (Summary Text)
2021
20217. Treatment with levothyroxine and testosterone ameliorated erectile dysfunction in a rat model of propylthiouracil-induced hypothyroidism
YILMAZ ORAL D., ASKER H., GÜVEN B., KIRLANGIÇ Ö. F., ÖZTEKİN Ç. V., GÜR S.
22nd Annual Fall Scientific Meeting of SMSNA, United States Of America, 24 October 2021, (Summary Text)
2022
20228. The direct metabolic effects of carvedilol in control mice hearts and hypertrophied H9c2 cells
GÜVEN B., WAGG C. S., PERSAD K. L., SUN Q., ANDRE D. J., BEŞİKCİ A., et al.
Pediatrics Research Day, Edmonton, Canada, 06 April 2022, (Summary Text)
2022
20229. Cardiac Glucose Oxidation Rates are Depressed in Heart Failure with Preserved Ejection Fraction (HFpEF)
SUN Q., GÜVEN B., WAGG C. S., OLIVEIRA A. A., SILVER H., ZHANG L., et al.
Pediatrics Research Day, Edmonton, Canada, 06 April 2022, (Summary Text)
2021
202110. Treatment with levothyroxine and testosterone ameliorated erectile dysfunction in rat model of propylthiouracil-induced hypothyroidism
KORKMAZ F., YILMAZ ORAL D., ASKER H., GÜVEN B., TÜRKCAN D., KIRLANGIÇ Ö. F., et al.
22nd Annual Fall Scientific Meeting of SMSNA, Scottsdale, United States Of America, 21 - 24 October 2021, vol.19, pp.30-31, (Summary Text)
2021
202111. CURCUMIN LOADED SEMISOLID SLN DISPERSIONS: FORMULATION OPTIMIZATION AND IN VIVO EVALUATION
KARGILI ŞEN A., BADILLI F. U., YEĞEN G., GÜVEN B., AKSU N. B., BEŞİKCİ A.
13th International Symposium on Pharmaceutical Sciences (ISOPS-13), Turkey, 22 June 2021, (Summary Text)
2019
201912. Design and Synthesis of Some Oxadiazole Bearing Benzimidazole Derivatives as PotentialEpidermal Growth Factor Receptor (EGFR) Inhibitors
ÇELİK İ., KILCIGİL G., GÜVEN B., BEŞİKCİ A., Kara Z.
ICMBC 2019 : International Conference onMedicinal and Biological Chemistry, Barselona, Spain, 15 - 16 August 2019, (Summary Text)
2019
201913. Metabolic effects of carvedilol through β-arrestin-2: investigations in cells and streptozotocin-diabetic rats
GÜVEN B., KARA Z., BEŞİKCİ A.
17th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), 23 - 26 June 2019, (Summary Text)
2018
201814. Presence of HCN Channels in Rat Aorta and Prevention of Endothelial Dysfunction with Their Selective Inhibitor Ivabradine
kara z., GÜVEN B., BEŞİKCİ A.
Pharmacology 2018, Londrina, Brazil, 17 - 19 December 2018, (Summary Text)
2018
201815. Synthesis of Some Thiadiazole/Triazole Linked1H-Benzimidazole Derivatives As Inhibitors of EGFR Tyrosine Kinase
ÇELİK İ., KILCIGİL G., BEŞİKCİ A., kara z., GÜVEN B.
Eczacılık Kongre ve Fuarı, Paris, France, 20 - 21 August 2018, (Summary Text)
2018
201816. THE EFFECT OF CARVEDILOL TREATMENT ON ERECTILE DYSFUNCTION IN STREPTOZOTOCIN INDUCED DIABETIC RATS.
YILMAZ D., GÜVEN B., KARA Z., GÜR S., BEŞİKCİ A.
12th INTERNATIONAL SYMPOSIUM ON PHARMACEUTICAL SCIENCES, Ankara, Turkey, 26 - 29 June 2018, (Summary Text)
2018
201817. THE POSSIBLE BENEFICIAL EFFECT OF IVABRADINE TREATMENT ON ERECTILE TISSUE IN A DIABETIC RAT MODEL
YILMAZ D., KARA Z., GÜVEN B., BEŞİKCİ A., GÜR S.
12th INTERNATIONAL SYMPOSIUM ON PHARMACEUTICAL SCIENCES, Ankara, Turkey, 26 - 29 June 2018, (Summary Text)
2017
201718. SYNTHESIS OF SOME 1H-BENZIMIDAZOLES CONTAINING CYCLOHEXYL SUBSTITUTED THIOSEMICARBAZIDES, TRIAZOLES, THIADIAZOLES AS INHIBITORS OF EGFR TYROSINE KINASE
ÇELİK İ., KILCIGİL G., Kara Z., GÜVEN B., BEŞİKCİ A.
GPSS2017, 11 - 13 October 2017, (Summary Text)
2016
201619. Investigation of the Pleiotropic Vascular Effects of Ivabradine in Control and Diabetic Rats
Kara Z., GÜVEN B., BEŞİKCİ A.
20th Annual Meeting of European Council for Cardiovascular Resarch, ECCR, Verona, Italy, 14 - 16 October 2016
Books
2023
20231. Beta Arrestin
BEŞİKCİ A., GÜVEN B.
in: Kalp Yetersizliği ve Tedavisinde Yeni Hedefler, , Editor, Tükiye Klinikleri, pp.159-161, 2023
2021
20212. Herpes Enfeksiyonlarında Kullanılan İlaçlar
GÜVEN B., ARSLAN E., BEŞİKCİ A.
in: Viral Enfeksiyonlarda Güncel Tedavi Yaklaşımları ve İmmünizasyon, Erdinç Meral, Editor, Ortadoğu, Ankara, pp.61-68, 2021
2021
20213. C Vitamini, D Vitamini, Çinko: COVID-19 Tedavisinde Mikro Besinlerden Makro Beklenti Gerçekçi mi?
GÜVEN B., Kara Z., BEŞİKCİ A.
in: Türkiye Klinikleri, Birengel Serhat, Balık İsmail, Editor, Ortadoğu, Ankara, pp.53-58, 2021
Funded Projects
2025 - Present
2025 - PresentGLP-1 Analoğu Semaglutidin Kontrol ve MASLD Sıçan Aortları Üzerindeki Etkisinin Değerlendirilmesi
Project Supported by Higher Education Institutions , BAP Other
GÜVEN ÇİLOĞLU B. (Executive), ISMAEL A. I. I., KOŞUMCU N. S.
2024 - Present
2024 - PresentParenteral kullanım için yeni fosfomisin formülasyonları: sentez, farmakokinetik analiz ve in silico değerlendirmeler
Project Supported by Higher Education Institutions , BAP PhD
BEŞİKCİ A. (Executive), ÖZYOL ADANIR Ö., KILCIGİL G., ÇINAR G., IRMAK N. E., GÜVEN ÇİLOĞLU B.
2023 - 2026
2023 - 2026Investigation of Inflammatory Signaling Pathways in the Heart and Aorta in a Heart Failure with Preserved Ejection Fraction Model: The Effect of Ketone Usage and GPR109A Receptors
TUBITAK Project , 3501 - National Young Researcher Career Development Program
GÜVEN B. (Executive), BEŞİKCİ A., TERZİ O. S.
2022 - 2024
2022 - 2024FFAR4 agonisti TUG-891’in hiperglisemik koşullarda H9c2 kardiyomiyoblast hücrelerde gevşeme yolağı bileşenleri üzerine etkisinin incelenmesi
Project Supported by Higher Education Institutions , BAP Research Project
Güven B.
2021 - 2023
2021 - 2023SARS-CoV-2 Main proteaz (Mpro) inhibitörü yeni benzimidazol türevlerinin in silico tasarım, sentez ve biyolojik aktivite değerlendirilmesi
Project Supported by Higher Education Institutions , BAP Research Project
Kılcıgil G. (Executive), Beşikci A., Güven Çiloğlu B., Şen H. T., Çelik İ.
Awards
Scholarships
2021 - 2022
2021 - 20222219
TUBITAK
2014 - 2018
2014 - 2018