Prof. Dr. HASAN ONGUN ONARAN

Yayın Ağı

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Community guidelines for GPCR ligand bias: IUPHAR review 32

Kolb P., Kenakin T., Alexander S. P. H., Bermudez M., Bohn L. M., Breinholt C. S., et al.

BRITISH JOURNAL OF PHARMACOLOGY , cilt.179, sa.14, ss.3651-3674, 2022 (SCI-Expanded)

Biased agonism at G protein-coupled receptors

Nagi K., ONARAN H. O.

CELLULAR SIGNALLING , cilt.83, 2021 (SCI-Expanded)

Conceptual and experimental issues in biased agonism

ONARAN H. O., Costa T.

CELLULAR SIGNALLING , cilt.82, 2021 (SCI-Expanded)

Vasopressin receptor 2 mutations in the nephrogenic syndrome of inappropriate antidiuresis show different mechanisms of constitutive activation for G protein coupled receptors

Vezzi V., Ambrosio C., Gro M. C., Molinari P., Sural G., Costa T., et al.

SCIENTIFIC REPORTS , cilt.10, sa.1, 2020 (SCI-Expanded)

Systematic errors in detecting biased agonism: Analysis of current methods and development of a new model-free approach

ONARAN H. O., Ambrosio C., UĞUR Ö., Koncz E. M., Gro M. C., Vezzi V., et al.

SCIENTIFIC REPORTS , cilt.7, 2017 (SCI-Expanded)

A Unifying Approach to the Duality of "Energetic" Versus "Conformational" Formulations of Allosteric Coupling: Mechanistic Implications for GPCR Allostery

ONARAN H. O., Costa T.

ALLOSTERISM IN DRUG DISCOVERY , cilt.56, ss.131-155, 2017 (SCI-Expanded)

What is biased efficacy? Defining the relationship between intrinsic efficacy and free energy coupling

ONARAN H. O., Rajagopal S., Costa T.

TRENDS IN PHARMACOLOGICAL SCIENCES , cilt.35, sa.12, ss.639-647, 2014 (SCI-Expanded)

Ligands Raise the Constraint That Limits Constitutive Activation in G Protein-coupled Opioid Receptors

Vezzi V., ONARAN H. O., Molinari P., Guerrini R., Balboni G., Calo G., et al.

JOURNAL OF BIOLOGICAL CHEMISTRY , cilt.288, sa.33, ss.23964-23978, 2013 (SCI-Expanded)

Where have all the active receptor states gone?

ONARAN H. O., Costa T.

NATURE CHEMICAL BIOLOGY , cilt.8, sa.8, ss.674-677, 2012 (SCI-Expanded)

Cell Contact-dependent Functional Selectivity of beta(2)-Adrenergic Receptor Ligands in Stimulating cAMP Accumulation and Extracellular Signal-regulated Kinase Phosphorylation

Kaya A. I., ONARAN H. O., Ozcan G., Ambrosio C., Costa T., Balli S., et al.

JOURNAL OF BIOLOGICAL CHEMISTRY , cilt.287, sa.9, ss.6362-6374, 2012 (SCI-Expanded)

Long and short distance movements of beta(2)-adrenoceptor in cell membrane assessed by photoconvertible fluorescent protein dendra2-beta(2)-adrenoceptor fusion

Kaya A. I., UĞUR Ö., Altuntas O., SAYAR K., ONARAN H. O.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH , cilt.1813, sa.8, ss.1511-1524, 2011 (SCI-Expanded)

beta(2)-Adrenoceptor, Gs and adenylate cyclase coupling in purified detergent-resistant, low density membrane fractions

Oner S. S., Kaya A. I., ONARAN H. O., Ozcan G., Ugur O.

EUROPEAN JOURNAL OF PHARMACOLOGY , cilt.630, sa.1-3, ss.42-52, 2010 (SCI-Expanded)

Coupling of beta 2-Adrenoceptors to XL alpha(s) and G alpha(s): A New Insight into Ligand-Induced G Protein Activation

Kaya A. I., Ugur Ö., Oener S. S., Bastepe M., ONARAN H. O.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS , cilt.329, sa.1, ss.350-359, 2009 (SCI-Expanded)

Allosteric Coupling and Conformational Fluctuations in Proteins

ONARAN H. O., Costa T.

CURRENT PROTEIN & PEPTIDE SCIENCE , cilt.10, sa.2, ss.110-115, 2009 (SCI-Expanded)

Long and short distance movements of beta 2-adrenoceptor in cell membrane assessed by photoconvertible fluorescent protein dendra-beta 2-adrenoceptor fusion

Kaya A., Altuntas O., Ugur O., ONARAN H. O.

FUNDAMENTAL & CLINICAL PHARMACOLOGY , cilt.22, ss.40, 2008 (SCI-Expanded)

Ability of beta-2 adrenoceptor ligands to selectively induce receptor mediated cAMP formation and ERK phosphorylation

Kaya A., ONARAN H. O., Ugur O.

FUNDAMENTAL & CLINICAL PHARMACOLOGY , cilt.22, ss.7, 2008 (SCI-Expanded)

Exploring allosteric coupling in the alpha-subunit of Heterotrimeric G proteins using evolutionary and ensemble-based approaches

SAYAR K., Ugur Ö., Liu T., Hilser V. J., ONARAN H. O.

BMC STRUCTURAL BIOLOGY , cilt.8, 2008 (SCI-Expanded)

Guanine nucleotide exchange-independent activation of G(s) protein by beta(2)-adrenoceptor

Ugur Ö., Oner S., Molinari P., Ambrosio C., Sayar K., ONARAN H. O.

MOLECULAR PHARMACOLOGY , cilt.68, sa.3, ss.720-728, 2005 (SCI-Expanded)

Gs in the caveola is coupled to adenylyl cyclase but not to beta 2-adrenergic receptor

Oner S. S., Ugur O., ONARAN H. O.

FUNDAMENTAL & CLINICAL PHARMACOLOGY , cilt.18, ss.39, 2004 (SCI-Expanded)

Intramolecular network of allosteric connectivity in GPCR: an improved evolutionary method combined with molecular dynamic simulations

ONARAN H. O., Ugur O., Fanelli F.

FUNDAMENTAL & CLINICAL PHARMACOLOGY , cilt.18, ss.76, 2004 (SCI-Expanded)

GDP-dependent activation of adenylate cyclase by beta(2)-adrenoceptor and Gs protein

Ugur O., Oner S. S., Molinari P., Ambrosio C., ONARAN H. O.

FUNDAMENTAL & CLINICAL PHARMACOLOGY , cilt.18, ss.78, 2004 (SCI-Expanded) Sürdürülebilir Kalkınma

Partial rescue of functional interactions of a nonpalmitoylated mutant of the G-protein G alpha(s) by fusion to the beta-adrenergic receptor

Ugur Ö., ONARAN H. O., Jones T.

BIOCHEMISTRY , cilt.42, sa.9, ss.2607-2615, 2003 (SCI-Expanded)

Correlation between affinity and efficacy - Response from Kenakin and Onaran

Kenakin T., ONARAN H. O.

TRENDS IN PHARMACOLOGICAL SCIENCES , cilt.24, sa.1, ss.5-6, 2003 (SCI-Expanded)

The ligand paradox between affinity and efficacy: can you be there and not make a difference?

Kenakin T., ONARAN H. O.

TRENDS IN PHARMACOLOGICAL SCIENCES , cilt.23, sa.6, ss.275-280, 2002 (SCI-Expanded)

Agonist-directed trafficking explaining the difference between response pattern of naratriptan and sumatriptan in rabbit common carotid artery

Akin D., ONARAN H. O., GÜRDAL H.

BRITISH JOURNAL OF PHARMACOLOGY , cilt.136, sa.2, ss.171-176, 2002 (SCI-Expanded)

Quasi-irreversible binding of agonist to beta-adrenoceptors and formation of non-dissociating receptor-G(s) complex in the absence of guanine nucleotides

ONARAN H. O., GÜRDAL H.

EUROPEAN JOURNAL OF PHARMACOLOGY , cilt.425, sa.3, ss.181-188, 2001 (SCI-Expanded) Sürdürülebilir Kalkınma

Dietary selenium and vitamin E intakes alter beta-adrenergic response of L-type Ca-current and beta-adrenoceptor-adenylate cyclase coupling in rat heart

Sayar K., Ugur M., GÜRDAL H., ONARAN H. O., Hotomaroglu O., Turan B.

JOURNAL OF NUTRITION , cilt.130, sa.4, ss.733-740, 2000 (SCI-Expanded)

Receptor dimerization and Hill coefficients - Reply

ONARAN H. O., GÜRDAL H.

TRENDS IN PHARMACOLOGICAL SCIENCES , cilt.20, sa.9, ss.358, 1999 (SCI-Expanded)

Ligand efficacy and affinity in an interacting 7TM receptor model

ONARAN H. O., GÜRDAL H.

TRENDS IN PHARMACOLOGICAL SCIENCES , cilt.20, sa.7, ss.274-278, 1999 (SCI-Expanded)

Pharmacokinetics of phenprobamate after oral administration to healthy subjects

Tulunay F., ONARAN H. O., Ergun H., Ucar A., Usanmaz S., Embil K., et al.

ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH , cilt.48, sa.11, ss.1068-1071, 1998 (SCI-Expanded)

Opioid receptor ligands in human hepatic encephalopathy

Yurdaydin C., Karavelioglu D., ONARAN H. O., Celik T., Yasa M., Uzunalimoglu O.

JOURNAL OF HEPATOLOGY , cilt.29, sa.5, ss.796-801, 1998 (SCI-Expanded)

Ca2+-induced inhibition of adenylyl cyclase in turkey erythrocyte membranes

Demirel E., Ugur Ö., ONARAN H. O.

PHARMACOLOGY , cilt.57, sa.4, ss.222-228, 1998 (SCI-Expanded)

Decrease in apparent alpha(1)-adrenoceptor G protein coupling during maturation in rat aorta

GÜRDAL H., Friedman E., Johnson M., ONARAN H. O.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES , cilt.53, sa.4, 1998 (SCI-Expanded)

The effects of verapamil and nimodipine on bupivacaine-induced cardiotoxicity in rats: An in vivo and in vitro study

Adsan H., Tulunay M., ONARAN H. O.

ANESTHESIA AND ANALGESIA , cilt.86, sa.4, ss.818-824, 1998 (SCI-Expanded)

Effect of dietary selenium intake on beta-adrenoceptor-adenylyl cyclase coupling in the membranes of rat heart.

Sayar K., Ugur M., Turan B., GÜRDAL H., ONARAN H. O.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY , cilt.358, sa.1, 1998 (SCI-Expanded)

Contribution of spontaneous beta-adrenoceptor activity in forskolin stimulated adenylyl cyclase activity in rat heart membranes.

Akin D., Tom B., ONARAN H. O., GÜRDAL H.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY , cilt.358, sa.1, 1998 (SCI-Expanded)

Contribution of spontaneous beta-adrenoceptor activity in forskolin stimulated adenylyl cyclase activity in rat heart membranes.

Akin D., Tom B., ONARAN H. O., GÜRDAL H.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY , cilt.358, sa.1, 1998 (SCI-Expanded)

An efficacy-dependent effect of cardiac overexpression of beta(2)-adrenoceptor on ligand affinity in transgenic mice

GÜRDAL H., Bond R., Johnson M., Friedman E., ONARAN H. O.

MOLECULAR PHARMACOLOGY , cilt.52, sa.2, ss.187-194, 1997 (SCI-Expanded)

Allosteric equilibrium model explains steady-state coupling of beta-adrenergic receptors to adenylate cyclase in turkey erythrocyte membranes

Ugur Ö., ONARAN H. O.

BIOCHEMICAL JOURNAL , cilt.323, ss.765-776, 1997 (SCI-Expanded)

Pharmacokinetics of recombinant human erythropoietin in children with chronic renal failure

ÇAKAR N., Ekim M., Tümer N., YALÇINKAYA F. F., Akar N., ONARAN H. O.

International Urology and Nephrology , cilt.29, sa.3, ss.377-383, 1997 (SCI-Expanded)

Agonist efficacy and allosteric models of receptor action

ONARAN H. O., Costa T.

RECEPTOR CLASSIFICATION , cilt.812, ss.98-115, 1997 (SCI-Expanded)

An efficacy-dependent effect of cardiac overexpression of β2- adrenoceptor on ligand affinity in transgenic mice

GÜRDAL H., Bond R. A., Johnson M. D., Friedman E., ONARAN H. O.

Molecular Pharmacology , cilt.52, sa.2, ss.187-194, 1997 (SCI-Expanded)

Opioid ligands in human hepatic encephalopathy.

Yurdaydin C., Karavelioglu D., Yasa H., ONARAN H. O.

HEPATOLOGY , cilt.24, sa.4, ss.1309, 1996 (SCI-Expanded)

Comparison of the effects of verapamil and nimodipine for prevention of bupivacaine cardiotoxicity using an isolated rat Langerdorff heart preparation:62.

Adsan H., Tulunay M., Turker R., ONARAN H. O.

European Journal of Anaesthesiology , cilt.13, sa.2, ss.188-189, 1996 (SCI-Expanded)

LYSOLIPIDS REVERSIBLY INHIBIT CA-2+-DEPENDENT, GTP-DEPENDENT AND PH-DEPENDENT FUSION OF BIOLOGICAL-MEMBRANES

CHERNOMORDIK L., VOGEL S., SOKOLOFF A., ONARAN H. O., LEIKINA E., ZIMMERBERG J.

FEBS LETTERS , cilt.318, sa.1, ss.71-76, 1993 (SCI-Expanded)

BETA-GAMMA SUBUNITS OF GUANINE NUCLEOTIDE-BINDING PROTEINS AND REGULATION OF SPONTANEOUS RECEPTOR ACTIVITY - THERMODYNAMIC MODEL FOR THE INTERACTION BETWEEN RECEPTORS AND GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNITS

ONARAN H. O., COSTA T., RODBARD D.

MOLECULAR PHARMACOLOGY , cilt.43, sa.2, ss.245-256, 1993 (SCI-Expanded)

βγ Subunits of guanine nucleotide-binding proteins and regulation of spontaneous receptor activity: Thermodynamic model for the interaction between receptors and guanine nucleotide-binding protein subunits

ONARAN H. O., Costa T., Rodbard D.

Molecular Pharmacology , cilt.43, sa.2, ss.245-256, 1993 (SCI-Expanded) Sürdürülebilir Kalkınma

ACIDIC PH INDUCES FUSION OF CELLS INFECTED WITH BACULOVIRUS TO FORM SYNCYTIA

LEIKINA E., ONARAN H. O., ZIMMERBERG J.

FEBS LETTERS , cilt.304, sa.2-3, ss.221-224, 1992 (SCI-Expanded)

DRUG EFFICACY AT GUANINE NUCLEOTIDE-BINDING REGULATORY PROTEIN-LINKED RECEPTORS - THERMODYNAMIC INTERPRETATION OF NEGATIVE ANTAGONISM AND OF RECEPTOR ACTIVITY IN THE ABSENCE OF LIGAND

COSTA T., OGINO Y., MUNSON P., ONARAN H. O., RODBARD D.

MOLECULAR PHARMACOLOGY , cilt.41, sa.3, ss.549-560, 1992 (SCI-Expanded)

ROLE OF ALPHA-ADRENOCEPTORS IN THE EFFECTS OF BUSPIRONE AND 5-CARBOXAMIDOTRYPTAMINE IN RABBIT ISOLATED THORACIC AORTA

GÜRDAL H., ONARAN H. O., TULUNAY F.

GENERAL PHARMACOLOGY , cilt.23, sa.1, ss.43-47, 1992 (SCI-Expanded)

ATYPICAL SCHILD PLOTS WITH HISTAMINE H-1 RECEPTOR AGONISTS AND ANTAGONISTS IN THE RABBIT AORTA

BOKESOY T., ONARAN H. O.

EUROPEAN JOURNAL OF PHARMACOLOGY , cilt.197, sa.1, ss.49-56, 1991 (SCI-Expanded)

REGIONAL HISTAMINERGIC POTENCIES IN RABBIT SYSTEMIC CIRCULATION

GURBUZ H., ONARAN H. O., BOKESOY T.

GENERAL PHARMACOLOGY , cilt.22, sa.4, ss.659-661, 1991 (SCI-Expanded)

KINETICS OF ANTAGONISM AT HISTAMINE-H1 RECEPTORS IN ISOLATED RABBIT ARTERIES

ONARAN H. O., BOKESOY T.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY , cilt.341, sa.4, ss.316-323, 1990 (SCI-Expanded)

HETEROGENEITY OF HISTAMINE H-2-RECEPTOR MEDIATED RESPONSES IN THE RABBIT AORTA

ONARAN H. O., BOKESOY T.

AGENTS AND ACTIONS , cilt.24, sa.3-4, ss.250-254, 1988 (SCI-Expanded)

A SEMI-ITERATIVE METHOD FOR DERIVATION OF CONCENTRATION-RESPONSE PARAMETERS

ONARAN H. O., TUNCALI T., BOKESOY T.

JOURNAL OF PHARMACOLOGICAL METHODS , cilt.19, sa.1, ss.39-45, 1988 (SCI-Expanded)

Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar

Cerrahi servislerdeki asansörlerden elde edilen bakterilerin tanımlanması ve antimikrobiyal duyarlılıkları

ÖCAL D., KOZAN G., OKLAZ A., KÖSE M. N., KIRCA İ., KILIÇ Ş., et al.

İnfeksiyon Dünyası Çalıştayı 2022, Ankara, Türkiye, 23 - 27 Mart 2022, ss.122-123

Kitap & Kitap Bölümleri

A Unifying Approach tothe Duality of “Energetic”Versus “Conformational”Formulations of AllostericCoupling: MechanisticImplications for GPCR Allostery

Onaran H. O., Costa T.

Allosterism in Drug Discovery, Dario Doller, Editör, Royal Society of Chemistry , Londrina, ss.131-155, 2017

Intramolecular dynamics and ligand-induced conformational changes: a stochastic model of receptor action

ONARAN H. O., costa t.

Biomedical Applications of Computer Modelling, Christopoulos A, Editör, CRC Press, New York, ss.109-134, 2001

A look into receptor efficacy. From the signalling network of the cell to the intramolecular motion of the receptor.

ONARAN H. O., Scheer A., cotecchia S., Costa T.

Handbook of Experimental Pharmacology vol 148, Kenakin TP, Agnus J, Editör, Springer, Berlin, ss.217-259, 2000

Metrikler

Yayın

Atıf (WoS)

1151

H-İndeks (WoS)

Atıf (Scopus)

1173

H-İndeks (Scopus)

Atıf (Scholar)

H-İndeks(Scholar)

Proje

Tez Danışmanlığı

Açık Erişim

BM Sürdürülebilir Kalkınma Amaçları

Yayınlar & Eserler

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar

Kitap & Kitap Bölümleri

Metrikler

Yayın

Atıf (WoS)

H-İndeks (WoS)

Atıf (Scopus)

H-İndeks (Scopus)

Atıf (Scholar)

H-İndeks(Scholar)

Proje

Tez Danışmanlığı

Açık Erişim