Doç. Dr. AYŞEGÜL DURAK
Ana Sayfa
Eğitim Bilgileri
Araştırma Alanları
Akademik İdari Deneyim
Yayınlar & Eserler
Proje & Patent & Tasarım
Bilimsel Faaliyetler
Başarılar & Tanınırlık
Duyurular & Dokümanlar
İletişim
Özgeçmiş Dosyası İndir
Türkçe
English
Ankara Üniversitesi
Akademik Veri Yönetim Sistemi
English
Akademik Veri Yönetim Sistemi
English
Yayınlar & Eserler
Yayın Ağı
SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler
The effects of cisplatin and jaceosidin on SH-SY5Y neuroblastoma cells: an electron microscopic, molecular and biochemical study
BAYRAM P.
,
AKSAK KARAMEŞE S.
,
oezdemir B.
,
DURAK A.
,
BİLLUR D.
ULTRASTRUCTURAL PATHOLOGY
, 2023 (SCI-Expanded)
Liraglutide provides cardioprotection through the recovery of mitochondrial dysfunction and oxidative stress in aging hearts
DURAK A.
,
TURAN B.
Journal of Physiology and Biochemistry
, cilt.79, sa.2, ss.297-311, 2023 (SCI-Expanded)
Comparisons of pleiotropic effects of SGLT2 inhibition and GLP-1 agonism on cardiac glucose intolerance in heart dysfunction
TURAN B.
,
DURAK A.
,
OLĞAR Y.
,
TUNCAY E.
MOLECULAR AND CELLULAR BIOCHEMISTRY
, cilt.477, sa.11, ss.2609-2625, 2022 (SCI-Expanded)
STIM1-Orai1 interaction mediated calcium influx activation contributes to cardiac contractility of insulin-resistant rats
DURAK A.
,
OLĞAR Y.
,
Genc K.
,
TUNCAY E.
,
AKAT F.
,
DEĞİRMENCİ S.
, et al.
BMC CARDIOVASCULAR DISORDERS
, cilt.22, sa.1, 2022 (SCI-Expanded)
Insulin acts as an atypical KCNQ1/KCNE1-current activator and reverses long QT in insulin-resistant aged rats by accelerating the ventricular action potential repolarization through affecting the beta(3)-adrenergic receptor signaling pathway
OLĞAR Y.
,
DURAK A.
,
Bitirim C. V.
,
TUNCAY E.
,
Turan B.
JOURNAL OF CELLULAR PHYSIOLOGY
, cilt.237, sa.2, ss.1353-1371, 2022 (SCI-Expanded)
Glucagon-like peptide-1 receptor agonist treatment of high carbohydrate intake-induced metabolic syndrome provides pleiotropic effects on cardiac dysfunction through alleviations in electrical and intracellular Ca2+ abnormalities and mitochondrial dysfunction
Durak A.
,
Akkuş E.
,
Gökçay Canpolat A.
,
Tuncay E.
,
Çorapçıoğlu D.
,
Turan B.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
, cilt.49, ss.46-59, 2022 (SCI-Expanded)
Ticagrelor alleviates high-carbohydrate intake induced altered electrical activity of ventricular cardiomyocytes by regulating sarcoplasmic reticulum-mitochondria miscommunication
OLĞAR Y.
,
DURAK A.
,
Degirmenci S.
,
TUNCAY E.
,
BİLLUR D.
,
ÖZDEMİR S.
, et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY
, cilt.476, sa.10, ss.3827-3844, 2021 (SCI-Expanded)
The Relationship Between Metabolic Syndrome Development and Tissue Trace Elements Status and Inflammatory Markers
Akdas S.
,
Turan B.
,
DURAK A.
,
ARIBAL AYRAL P.
,
YAZIHAN N.
BIOLOGICAL TRACE ELEMENT RESEARCH
, cilt.198, sa.1, ss.16-24, 2020 (SCI-Expanded)
Titin and CK2 alpha are New Intracellular Targets in Acute Insulin Application-Associated Benefits on Electrophysiological Parameters of Left Ventricular Cardiomyocytes From Insulin-Resistant Metabolic Syndrome Rats
DURAK A.
,
Bitirim C. V.
,
Turan B.
CARDIOVASCULAR DRUGS AND THERAPY
, cilt.34, sa.4, ss.487-501, 2020 (SCI-Expanded)
Ticagrelor reverses the mitochondrial dysfunction through preventing accumulated autophagosomes-dependent apoptosis and ER stress in insulin-resistant H9c2 myocytes
OLĞAR Y.
,
TUNCAY E.
,
BİLLUR D.
,
DURAK A.
,
ÖZDEMİR S.
,
Turan B.
MOLECULAR AND CELLULAR BIOCHEMISTRY
, cilt.469, sa.1-2, ss.97-107, 2020 (SCI-Expanded)
beta(3)-adrenergic receptor activation plays an important role in the depressed myocardial contractility via both elevated levels of cellular free Zn2+ and reactive nitrogen species
TUNCAY E.
,
OLĞAR Y.
,
DURAK A.
,
Degirmenci S.
,
BİTİRİM C. V.
,
Turan B.
JOURNAL OF CELLULAR PHYSIOLOGY
, cilt.234, sa.8, ss.13370-13386, 2019 (SCI-Expanded)
Zn2+-transporters ZIP7 and ZnT7 play important role in progression of cardiac dysfunction via affecting sarco(endo)plasmic reticulum-mitochondria coupling in hyperglycemic cardiomyocytes
TUNCAY E.
,
BİTİRİM C. V.
,
OLĞAR Y.
,
DURAK A.
,
Rutter G. A.
,
Turan B.
MITOCHONDRION
, cilt.44, ss.41-52, 2019 (SCI-Expanded)
A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats
DURAK A.
,
OLĞAR Y.
,
Degirmenci S.
,
AKKUŞ E.
,
TUNCAY E.
,
Turan B.
CARDIOVASCULAR DIABETOLOGY
, cilt.17, 2018 (SCI-Expanded)
Aging related functional and structural changes in the heart and aorta: MitoTEMPO improves aged-cardiovascular performance
OLĞAR Y.
,
DEĞİRMENCİ S.
,
DURAK A.
,
BİLLUR D.
,
CAN B.
,
KAYKI MUTLU G.
, et al.
Experimental Gerontology
, cilt.110, ss.172-181, 2018 (SCI-Expanded)
An Investigation on Molecular Basis of the Effects of SGLT2 İnhibitor Dapagliflozin on Hyperglycemia-Associated Heart Dysfunction*
DURAK A.
,
OLĞAR Y.
,
DEĞİRMENCİ S.
,
Ertürk N.
,
akbaş M. t.
,
aygün a.
, et al.
JOURNAL OF CELLULAR PHYSIOLOGY
, cilt.71, 2018 (SCI-Expanded)
Intermittent hypoxia induces beneficial cardiovascular remodeling in left ventricular function of type 1 diabetic rat
AKAT F.
,
FIÇICILAR H.
,
DURAK A.
,
TUNCAY E.
,
Dursun A. D.
,
TOPAL ÇELİKKAN F.
, et al.
ANATOLIAN JOURNAL OF CARDIOLOGY
, cilt.19, sa.4, ss.259-266, 2018 (SCI-Expanded)
Increased free Zn2+ correlates induction of sarco(endo)plasmic reticulum stress via altered expression levels of Zn2+-transporters in heart failure
OLĞAR Y.
,
DURAK A.
,
TUNCAY E.
,
BİTİRİM C. V.
,
ÖZÇINAR E.
,
İNAN M. B.
, et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
, cilt.22, sa.3, ss.1944-1956, 2018 (SCI-Expanded)
Cytosolic increased labile Zn2+ contributes to arrhythmogenic action potentials in left ventricular cardiomyocytes through protein thiol oxidation and cellular ATP depletion
DEĞİRMENCİ S.
,
OLĞAR Y.
,
DURAK A.
,
TUNCAY E.
,
Turan B.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
, cilt.48, ss.202-212, 2018 (SCI-Expanded)
Onset of decreased heart work is correlated with increased heart rate and shortened QT interval in high-carbohydrate fed overweight rats
DURAK A.
,
OLĞAR Y.
,
TUNCAY E.
,
Karaomerlioglu I.
,
Mutlu G.
,
ARIOĞLU İNAN E.
, et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
, cilt.95, sa.11, ss.1335-1342, 2017 (SCI-Expanded)
Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart
TUNCAY E.
,
BİTİRİM C. V.
,
DURAK A.
,
Carrat G. R. J.
,
Taylor K. M.
,
Rutter G. A.
, et al.
DIABETES
, cilt.66, sa.5, ss.1346-1358, 2017 (SCI-Expanded)
Interplay Between Cytosolic Free Zn2+ and Mitochondrion Morphological Changes in Rat Ventricular Cardiomyocytes
BİLLUR D.
,
TUNCAY E.
,
Okatan E. N.
,
OLĞAR Y.
,
Durak A.
,
DEĞİRMENCİ S.
, et al.
BIOLOGICAL TRACE ELEMENT RESEARCH
, cilt.174, sa.1, ss.177-188, 2016 (SCI-Expanded)
Both Reactive ROS and RNS Contribute to Intracellular Free Zn2+ Regulation in Cardiomyocytes Via Zinc Transporter ZIP7 Under Hyperglycemia
TUNCAY E.
,
Bitirim V.
,
DURAK A.
,
Rutter G. A.
,
Turan B.
FREE RADICAL BIOLOGY AND MEDICINE
, cilt.100, 2016 (SCI-Expanded)
Electrophysiological basis of metabolic-syndrome-induced cardiac dysfunction
Okatan E. N.
,
Durak A.
,
Turan B.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
, cilt.94, sa.10, ss.1064-1073, 2016 (SCI-Expanded)
Immuno-spin trapping detection of antioxidant/pro-oxidant properties of zinc or selenium on DNA and protein radical formation via hydrogen peroxide
Deletioglu V.
,
TUNCAY E.
,
Toy A.
,
Atalay M.
,
Turan B.
MOLECULAR AND CELLULAR BIOCHEMISTRY
, cilt.409, sa.1-2, ss.23-31, 2015 (SCI-Expanded)
Beta-blocker timolol alleviates hyperglycemia-induced cardiac damage via inhibition of endoplasmic reticulum stress
ÇİÇEK F.
,
Toy A.
,
TUNCAY E.
,
CAN B.
,
Turan B.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
, cilt.46, sa.5, ss.377-387, 2014 (SCI-Expanded)
Enhancement of Cellular Antioxidant-Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn2+ and Ca2+ and Prevention of RyR2-Leak in Hyperglycemic Cardiomyocytes
TUNCAY E.
,
Okatan E. N.
,
Toy A.
,
Turan B.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
, cilt.2014, 2014 (SCI-Expanded)
Diğer Dergilerde Yayınlanan Makaleler
Investigation of the Effect of the Antiaggregant Agent Ticagrelor on the Electrical and Mechanical Activities of Rat Heart With Type 1 Diabetes
DURAK A.
,
TUNCAY E.
,
DEĞİRMENCİ S.
,
TURAN B.
Ankara Üniversitesi Tıp Fakültesi Mecmuası
, 2021 (Hakemli Dergi)
Pioglitazonun Metabolik Sendromlu Sıçan Kalp Fonksiyonuna Etkisinin Elektrofizyolojik Yöntemlerle İncelenmesi
DURAK A.
,
TUTAR SELÇUK M. F.
,
OLĞAR Y.
,
OKATAN E. N.
,
DEĞİRMENCİ S.
,
aksu s.
, et al.
Ankara Üniversitesi Tıp Fakültesi Mecmuası
, 2015 (Hakemli Dergi)
Metrikler
Daha fazla metrik
Yayın
57
Atıf (WoS)
456
H-İndeks (WoS)
12
Atıf (Scopus)
452
H-İndeks (Scopus)
12
Proje
3
Açık Erişim
11
BM Sürdürülebilir Kalkınma Amaçları