Doç. Dr. AYŞEGÜL DURAK

1. Acute GLP-1 Agonism Induces Arrhythmogenic Electrical Activity in Aged Mice Heart Through Impaired Cellular Na+ and Ca2+ Handlings: The Role of CK2 Hyperphosphorylation

OLĞAR Y., DURAK A., TURAN B.

Anatolian Journal of Cardiology , cilt.29, sa.2, ss.83-94, 2025 (SCI-Expanded)

2. Liraglutide provides cardioprotection through the recovery of mitochondrial dysfunction and oxidative stress in aging hearts

DURAK A., TURAN B.

Journal of Physiology and Biochemistry , cilt.79, sa.2, ss.297-311, 2023 (SCI-Expanded, Scopus)

3. The effects of cisplatin and jaceosidin on SH-SY5Y neuroblastoma cells: an electron microscopic, molecular and biochemical study

BAYRAM P., AKSAK KARAMEŞE S., oezdemir B., DURAK A., BİLLUR D.

ULTRASTRUCTURAL PATHOLOGY , 2023 (SCI-Expanded, Scopus)

4. Comparisons of pleiotropic effects of SGLT2 inhibition and GLP-1 agonism on cardiac glucose intolerance in heart dysfunction

TURAN B., DURAK A., OLĞAR Y., TUNCAY E.

MOLECULAR AND CELLULAR BIOCHEMISTRY , cilt.477, sa.11, ss.2609-2625, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

5. STIM1-Orai1 interaction mediated calcium influx activation contributes to cardiac contractility of insulin-resistant rats

DURAK A., OLĞAR Y., Genc K., TUNCAY E., AKAT F., DEĞİRMENCİ S., et al.

BMC CARDIOVASCULAR DISORDERS , cilt.22, sa.1, 2022 (SCI-Expanded, Scopus)

6. Insulin acts as an atypical KCNQ1/KCNE1-current activator and reverses long QT in insulin-resistant aged rats by accelerating the ventricular action potential repolarization through affecting the beta(3)-adrenergic receptor signaling pathway

OLĞAR Y., DURAK A., Bitirim C. V., TUNCAY E., Turan B.

JOURNAL OF CELLULAR PHYSIOLOGY , cilt.237, sa.2, ss.1353-1371, 2022 (SCI-Expanded, Scopus)

7. Glucagon-like peptide-1 receptor agonist treatment of high carbohydrate intake-induced metabolic syndrome provides pleiotropic effects on cardiac dysfunction through alleviations in electrical and intracellular Ca2+ abnormalities and mitochondrial dysfunction

Durak A., Akkuş E., Gökçay Canpolat A., Tuncay E., Çorapçıoğlu D., Turan B.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY , cilt.49, ss.46-59, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

8. Ticagrelor alleviates high-carbohydrate intake induced altered electrical activity of ventricular cardiomyocytes by regulating sarcoplasmic reticulum-mitochondria miscommunication

OLĞAR Y., DURAK A., Degirmenci S., TUNCAY E., BİLLUR D., ÖZDEMİR S., et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY , cilt.476, sa.10, ss.3827-3844, 2021 (SCI-Expanded, Scopus)

9. Investigation of the Effect of the Antiaggregant Agent Ticagrelor on the Electrical and Mechanical Activities of Rat Heart With Type 1 Diabetes

DURAK A., TUNCAY E., DEĞİRMENCİ S., TURAN B.

Ankara Üniversitesi Tıp Fakültesi Mecmuası , 2021 (Hakemli Dergi)

10. The Relationship Between Metabolic Syndrome Development and Tissue Trace Elements Status and Inflammatory Markers

Akdas S., Turan B., DURAK A., ARIBAL AYRAL P., YAZIHAN N.

BIOLOGICAL TRACE ELEMENT RESEARCH , cilt.198, sa.1, ss.16-24, 2020 (SCI-Expanded, Scopus)

11. Titin and CK2 alpha are New Intracellular Targets in Acute Insulin Application-Associated Benefits on Electrophysiological Parameters of Left Ventricular Cardiomyocytes From Insulin-Resistant Metabolic Syndrome Rats

DURAK A., Bitirim C. V., Turan B.

CARDIOVASCULAR DRUGS AND THERAPY , cilt.34, sa.4, ss.487-501, 2020 (SCI-Expanded, Scopus)

12. Ticagrelor reverses the mitochondrial dysfunction through preventing accumulated autophagosomes-dependent apoptosis and ER stress in insulin-resistant H9c2 myocytes

OLĞAR Y., TUNCAY E., BİLLUR D., DURAK A., ÖZDEMİR S., Turan B.

MOLECULAR AND CELLULAR BIOCHEMISTRY , cilt.469, sa.1-2, ss.97-107, 2020 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

13. beta(3)-adrenergic receptor activation plays an important role in the depressed myocardial contractility via both elevated levels of cellular free Zn2+ and reactive nitrogen species

TUNCAY E., OLĞAR Y., DURAK A., Degirmenci S., BİTİRİM C. V., Turan B.

JOURNAL OF CELLULAR PHYSIOLOGY , cilt.234, sa.8, ss.13370-13386, 2019 (SCI-Expanded, Scopus)

14. Zn2+-transporters ZIP7 and ZnT7 play important role in progression of cardiac dysfunction via affecting sarco(endo)plasmic reticulum-mitochondria coupling in hyperglycemic cardiomyocytes

TUNCAY E., BİTİRİM C. V., OLĞAR Y., DURAK A., Rutter G. A., Turan B.

MITOCHONDRION , cilt.44, ss.41-52, 2019 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

15. A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats

DURAK A., OLĞAR Y., Degirmenci S., AKKUŞ E., TUNCAY E., Turan B.

CARDIOVASCULAR DIABETOLOGY , cilt.17, 2018 (SCI-Expanded, Scopus)

16. Aging related functional and structural changes in the heart and aorta: MitoTEMPO improves aged-cardiovascular performance

OLĞAR Y., DEĞİRMENCİ S., DURAK A., BİLLUR D., CAN B., KAYKI MUTLU G., et al.

Experimental Gerontology , cilt.110, ss.172-181, 2018 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

17. An Investigation on Molecular Basis of the Effects of SGLT2 İnhibitor Dapagliflozin on Hyperglycemia-Associated Heart Dysfunction*

DURAK A., OLĞAR Y., DEĞİRMENCİ S., Ertürk N., akbaş M. t., aygün a., et al.

JOURNAL OF CELLULAR PHYSIOLOGY , cilt.71, 2018 (SCI-Expanded)

18. Intermittent hypoxia induces beneficial cardiovascular remodeling in left ventricular function of type 1 diabetic rat

AKAT F., FIÇICILAR H., DURAK A., TUNCAY E., Dursun A. D., TOPAL ÇELİKKAN F., et al.

ANATOLIAN JOURNAL OF CARDIOLOGY , cilt.19, sa.4, ss.259-266, 2018 (SCI-Expanded, Scopus, TRDizin)

19. Increased free Zn2+ correlates induction of sarco(endo)plasmic reticulum stress via altered expression levels of Zn2+-transporters in heart failure

OLĞAR Y., DURAK A., TUNCAY E., BİTİRİM C. V., ÖZÇINAR E., İNAN M. B., et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE , cilt.22, sa.3, ss.1944-1956, 2018 (SCI-Expanded, Scopus)

20. Cytosolic increased labile Zn2+ contributes to arrhythmogenic action potentials in left ventricular cardiomyocytes through protein thiol oxidation and cellular ATP depletion

DEĞİRMENCİ S., OLĞAR Y., DURAK A., TUNCAY E., Turan B.

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY , cilt.48, ss.202-212, 2018 (SCI-Expanded, Scopus)

21. Onset of decreased heart work is correlated with increased heart rate and shortened QT interval in high-carbohydrate fed overweight rats

DURAK A., OLĞAR Y., TUNCAY E., Karaomerlioglu I., Mutlu G., ARIOĞLU İNAN E., et al.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY , cilt.95, sa.11, ss.1335-1342, 2017 (SCI-Expanded, Scopus)

22. Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart

TUNCAY E., BİTİRİM C. V., DURAK A., Carrat G. R. J., Taylor K. M., Rutter G. A., et al.

DIABETES , cilt.66, sa.5, ss.1346-1358, 2017 (SCI-Expanded, Scopus)

23. Interplay Between Cytosolic Free Zn2+ and Mitochondrion Morphological Changes in Rat Ventricular Cardiomyocytes

BİLLUR D., TUNCAY E., Okatan E. N., OLĞAR Y., Durak A., DEĞİRMENCİ S., et al.

BIOLOGICAL TRACE ELEMENT RESEARCH , cilt.174, sa.1, ss.177-188, 2016 (SCI-Expanded, Scopus)

24. Both Reactive ROS and RNS Contribute to Intracellular Free Zn2+ Regulation in Cardiomyocytes Via Zinc Transporter ZIP7 Under Hyperglycemia

TUNCAY E., Bitirim V., DURAK A., Rutter G. A., Turan B.

FREE RADICAL BIOLOGY AND MEDICINE , cilt.100, 2016 (SCI-Expanded, Scopus)

25. Electrophysiological basis of metabolic-syndrome-induced cardiac dysfunction

Okatan E. N., Durak A., Turan B.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY , cilt.94, sa.10, ss.1064-1073, 2016 (SCI-Expanded, Scopus)

26. Immuno-spin trapping detection of antioxidant/pro-oxidant properties of zinc or selenium on DNA and protein radical formation via hydrogen peroxide

Deletioglu V., TUNCAY E., Toy A., Atalay M., Turan B.

MOLECULAR AND CELLULAR BIOCHEMISTRY , cilt.409, sa.1-2, ss.23-31, 2015 (SCI-Expanded, Scopus)

27. Pioglitazonun Metabolik Sendromlu Sıçan Kalp Fonksiyonuna Etkisinin Elektrofizyolojik Yöntemlerle İncelenmesi

DURAK A., TUTAR SELÇUK M. F., OLĞAR Y., OKATAN E. N., DEĞİRMENCİ S., aksu s., et al.

Ankara Üniversitesi Tıp Fakültesi Mecmuası , 2015 (Hakemli Dergi)

28. Beta-blocker timolol alleviates hyperglycemia-induced cardiac damage via inhibition of endoplasmic reticulum stress

ÇİÇEK F., Toy A., TUNCAY E., CAN B., Turan B.

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES , cilt.46, sa.5, ss.377-387, 2014 (SCI-Expanded, Scopus)

29. Enhancement of Cellular Antioxidant-Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn2+ and Ca2+ and Prevention of RyR2-Leak in Hyperglycemic Cardiomyocytes

TUNCAY E., Okatan E. N., Toy A., Turan B.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY , cilt.2014, 2014 (SCI-Expanded, Scopus)

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