Akademik Veri Yönetim Sistemi
Journal of Hygienic Engineering and Design, cilt.30, ss.17-25, 2019 (Scopus)
© 2019, Consulting and Training Center - KEY. All rights reserved.Inflammation plays an important role in the development of many diseases and health conditions. Because walnut has rich antioxidant content such as polyphe-nols, γ-tocopherol and melatonin, walnuts against these diseases may be at least partially attributed to their anti-inflammatory effect. When comprehensive prospective studies were evalu-ated, vascular endothelial molecules such as intracel-lular adhesion molecule 1 and vascular cell adhesion molecule 1 and eicosanoid levels such as prostaglan-din E2 and thromboxane A2 were found to be decreased after walnut-containing diet. In randomized controlled trials, it was found that c-reactive protein, interleukin-6, interleukin-1 and fibrinogen were reduced by approximately 5% in walnuts consumption of 30-65 grams per day. It has been found that walnut consumption in healthy, obese or diabetic individuals increases the concentration of adiponectin, which is anti-inflammatory cytokine, and consequently con-tributes to decrease in pro-inflammatory precursor molecules. Walnut can also increase nitric oxide syn-thesis, which can prevent oxygen mediated inflamma-tion, due to its rich arginine content. Given the small number of studies examining the effects walnuts, more trials are needed to address the effects of walnuts on inflammation or cardiovascular risk. Although some pharmacologic treatments and exercise appear to be effective in reducing inflammation, healthy diets that include regular consumption of walnuts may pro-tect against the possible consequences of low-grade inflammation. Finally, walnut contain alpha linolenic acid, polyphe-nol, melatonin and arginine. Lysine rate is higher than other different types of nuts, so it is important to con-duct research on the effect of walnut consumption on inflammation.