Metrikler
Yayın
59
Açık Erişim
11
BM Sürdürülebilir Kalkınma Amaçları
Eğitim Bilgileri
2012 - 2018
2012 - 2018Doktora
Ankara Üniversitesi, Sağlık Bilimleri Enstitüsü, Biyofizik (Dr) (Tıp), Türkiye
2010 - 2012
2010 - 2012Yüksek Lisans
Trakya Üniversitesi, Sağlık Bilimleri Enstitüsü, Biyofizik (Yl) (Tezli), Türkiye
2005 - 2009
2005 - 2009Lisans
Trakya Üniversitesi, Fen-Edebiyat Fakültesi, Fizik Pr., Türkiye
Yaptığı Tezler
2018
2018Doktora
İnsülin direnci gelişmiş sıçan kardiyomiyositlerinde sarkolemmal iyon kanallarının fonksiyon ve yapısının elektrofizyolojik ve moleküler biyolojik tekniklerle incelenmesi
Ankara Üniversitesi, Sağlık Bilimleri Enstitüsü, Biyofizik (Dr) (Tıp)
2013
2013Yüksek Lisans
Meme kanserli hastalarda tedavi öncesi ve sonrası total antioksidan kapasite, eser elementler ve lipit peroksidasyonu 
Trakya Üniversitesi, Sağlık Bilimleri Enstitüsü, Biyofizik (Yl) (Tezli)
Yabancı Diller
B2 Orta Üstü
B2 Orta Üstüİngilizce
Araştırma Alanları
Temel Tıp Bilimleri
Makaleler
Tümü (29)
SCI-E, SSCI, AHCI (27)
SCI-E, SSCI, AHCI, ESCI (27)
Scopus (27)
TRDizin (4)
2025
20251. Acute GLP-1 Agonism Induces Arrhythmogenic Electrical Activity in Aged Mice Heart Through Impaired Cellular Na+ and Ca2+ Handlings: The Role of CK2 Hyperphosphorylation
OLĞAR Y., DURAK A., TURAN B.
Anatolian Journal of Cardiology
, cilt.29, sa.2, ss.83-94, 2025 (SCI-Expanded, Scopus, TRDizin)
2023
20232. Liraglutide provides cardioprotection through the recovery of mitochondrial dysfunction and oxidative stress in aging hearts
DURAK A., TURAN B.
Journal of Physiology and Biochemistry
, cilt.79, sa.2, ss.297-311, 2023 (SCI-Expanded, Scopus)
2023
20233. The effects of cisplatin and jaceosidin on SH-SY5Y neuroblastoma cells: an electron microscopic, molecular and biochemical study
BAYRAM P., AKSAK KARAMEŞE S., oezdemir B., DURAK A., BİLLUR D.
ULTRASTRUCTURAL PATHOLOGY
, 2023 (SCI-Expanded, Scopus)
2022
20224. Comparisons of pleiotropic effects of SGLT2 inhibition and GLP-1 agonism on cardiac glucose intolerance in heart dysfunction
TURAN B., DURAK A., OLĞAR Y., TUNCAY E.
MOLECULAR AND CELLULAR BIOCHEMISTRY
, cilt.477, sa.11, ss.2609-2625, 2022 (SCI-Expanded, Scopus)
2022
20225. STIM1-Orai1 interaction mediated calcium influx activation contributes to cardiac contractility of insulin-resistant rats
DURAK A., OLĞAR Y., Genc K., TUNCAY E., AKAT F., DEĞİRMENCİ S., et al.
BMC CARDIOVASCULAR DISORDERS
, cilt.22, sa.1, 2022 (SCI-Expanded, Scopus)
2022
20226. Insulin acts as an atypical KCNQ1/KCNE1-current activator and reverses long QT in insulin-resistant aged rats by accelerating the ventricular action potential repolarization through affecting the beta(3)-adrenergic receptor signaling pathway
OLĞAR Y., DURAK A., Bitirim C. V., TUNCAY E., Turan B.
JOURNAL OF CELLULAR PHYSIOLOGY
, cilt.237, sa.2, ss.1353-1371, 2022 (SCI-Expanded, Scopus)
2022
20227. Glucagon-like peptide-1 receptor agonist treatment of high carbohydrate intake-induced metabolic syndrome provides pleiotropic effects on cardiac dysfunction through alleviations in electrical and intracellular Ca2+ abnormalities and mitochondrial dysfunction
Durak A., Akkuş E., Gökçay Canpolat A., Tuncay E., Çorapçıoğlu D., Turan B.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
, cilt.49, ss.46-59, 2022 (SCI-Expanded, Scopus)
2021
20218. Ticagrelor alleviates high-carbohydrate intake induced altered electrical activity of ventricular cardiomyocytes by regulating sarcoplasmic reticulum-mitochondria miscommunication
OLĞAR Y., DURAK A., Degirmenci S., TUNCAY E., BİLLUR D., ÖZDEMİR S., et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY
, cilt.476, sa.10, ss.3827-3844, 2021 (SCI-Expanded, Scopus)
2021
20219. Investigation of the Effect of the Antiaggregant Agent Ticagrelor on the Electrical and Mechanical Activities of Rat Heart With Type 1 Diabetes
DURAK A., TUNCAY E., DEĞİRMENCİ S., TURAN B.
Ankara Üniversitesi Tıp Fakültesi Mecmuası , 2021 (TRDizin)
2020
202010. The Relationship Between Metabolic Syndrome Development and Tissue Trace Elements Status and Inflammatory Markers
Akdas S., Turan B., DURAK A., ARIBAL AYRAL P., YAZIHAN N.
BIOLOGICAL TRACE ELEMENT RESEARCH
, cilt.198, sa.1, ss.16-24, 2020 (SCI-Expanded, Scopus)
2020
202011. Titin and CK2 alpha are New Intracellular Targets in Acute Insulin Application-Associated Benefits on Electrophysiological Parameters of Left Ventricular Cardiomyocytes From Insulin-Resistant Metabolic Syndrome Rats
DURAK A., Bitirim C. V., Turan B.
CARDIOVASCULAR DRUGS AND THERAPY
, cilt.34, sa.4, ss.487-501, 2020 (SCI-Expanded, Scopus)
2020
202012. Ticagrelor reverses the mitochondrial dysfunction through preventing accumulated autophagosomes-dependent apoptosis and ER stress in insulin-resistant H9c2 myocytes
OLĞAR Y., TUNCAY E., BİLLUR D., DURAK A., ÖZDEMİR S., Turan B.
MOLECULAR AND CELLULAR BIOCHEMISTRY
, cilt.469, sa.1-2, ss.97-107, 2020 (SCI-Expanded, Scopus)
2019
201913. beta(3)-adrenergic receptor activation plays an important role in the depressed myocardial contractility via both elevated levels of cellular free Zn2+ and reactive nitrogen species
TUNCAY E., OLĞAR Y., DURAK A., Degirmenci S., BİTİRİM C. V., Turan B.
JOURNAL OF CELLULAR PHYSIOLOGY
, cilt.234, sa.8, ss.13370-13386, 2019 (SCI-Expanded, Scopus)
2019
201914. Zn2+-transporters ZIP7 and ZnT7 play important role in progression of cardiac dysfunction via affecting sarco(endo)plasmic reticulum-mitochondria coupling in hyperglycemic cardiomyocytes
TUNCAY E., BİTİRİM C. V., OLĞAR Y., DURAK A., Rutter G. A., Turan B.
MITOCHONDRION
, cilt.44, ss.41-52, 2019 (SCI-Expanded, Scopus)
2018
201815. A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats
DURAK A., OLĞAR Y., Degirmenci S., AKKUŞ E., TUNCAY E., Turan B.
CARDIOVASCULAR DIABETOLOGY
, cilt.17, 2018 (SCI-Expanded, Scopus)
2018
201816. Aging related functional and structural changes in the heart and aorta: MitoTEMPO improves aged-cardiovascular performance
OLĞAR Y., DEĞİRMENCİ S., DURAK A., BİLLUR D., CAN B., KAYKI MUTLU G., et al.
Experimental Gerontology
, cilt.110, ss.172-181, 2018 (SCI-Expanded, Scopus)
2018
201817. An Investigation on Molecular Basis of the Effects of SGLT2 İnhibitor Dapagliflozin on Hyperglycemia-Associated Heart Dysfunction*
DURAK A., OLĞAR Y., DEĞİRMENCİ S., Ertürk N., akbaş M. t., aygün a., et al.
JOURNAL OF CELLULAR PHYSIOLOGY , cilt.71, 2018 (SCI-Expanded, Scopus)
2018
201818. Intermittent hypoxia induces beneficial cardiovascular remodeling in left ventricular function of type 1 diabetic rat
AKAT F., FIÇICILAR H., DURAK A., TUNCAY E., Dursun A. D., TOPAL ÇELİKKAN F., et al.
ANATOLIAN JOURNAL OF CARDIOLOGY
, cilt.19, sa.4, ss.259-266, 2018 (SCI-Expanded, Scopus, TRDizin)
2018
201819. Increased free Zn2+ correlates induction of sarco(endo)plasmic reticulum stress via altered expression levels of Zn2+-transporters in heart failure
OLĞAR Y., DURAK A., TUNCAY E., BİTİRİM C. V., ÖZÇINAR E., İNAN M. B., et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
, cilt.22, sa.3, ss.1944-1956, 2018 (SCI-Expanded, Scopus)
2018
201820. Cytosolic increased labile Zn2+ contributes to arrhythmogenic action potentials in left ventricular cardiomyocytes through protein thiol oxidation and cellular ATP depletion
DEĞİRMENCİ S., OLĞAR Y., DURAK A., TUNCAY E., Turan B.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
, cilt.48, ss.202-212, 2018 (SCI-Expanded, Scopus)
2017
201721. Onset of decreased heart work is correlated with increased heart rate and shortened QT interval in high-carbohydrate fed overweight rats
DURAK A., OLĞAR Y., TUNCAY E., Karaomerlioglu I., Mutlu G., ARIOĞLU İNAN E., et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
, cilt.95, sa.11, ss.1335-1342, 2017 (SCI-Expanded, Scopus)
2017
201722. Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart
TUNCAY E., BİTİRİM C. V., DURAK A., Carrat G. R. J., Taylor K. M., Rutter G. A., et al.
DIABETES
, cilt.66, sa.5, ss.1346-1358, 2017 (SCI-Expanded, Scopus)
2016
201623. Interplay Between Cytosolic Free Zn2+ and Mitochondrion Morphological Changes in Rat Ventricular Cardiomyocytes
BİLLUR D., TUNCAY E., Okatan E. N., OLĞAR Y., Durak A., DEĞİRMENCİ S., et al.
BIOLOGICAL TRACE ELEMENT RESEARCH
, cilt.174, sa.1, ss.177-188, 2016 (SCI-Expanded, Scopus)
2016
201624. Both Reactive ROS and RNS Contribute to Intracellular Free Zn2+ Regulation in Cardiomyocytes Via Zinc Transporter ZIP7 Under Hyperglycemia
TUNCAY E., Bitirim V., DURAK A., Rutter G. A., Turan B.
FREE RADICAL BIOLOGY AND MEDICINE
, cilt.100, 2016 (SCI-Expanded, Scopus)
2016
201625. Electrophysiological basis of metabolic-syndrome-induced cardiac dysfunction
Okatan E. N., Durak A., Turan B.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
, cilt.94, sa.10, ss.1064-1073, 2016 (SCI-Expanded, Scopus)
2015
201526. Immuno-spin trapping detection of antioxidant/pro-oxidant properties of zinc or selenium on DNA and protein radical formation via hydrogen peroxide
Deletioglu V., TUNCAY E., Toy A., Atalay M., Turan B.
MOLECULAR AND CELLULAR BIOCHEMISTRY
, cilt.409, sa.1-2, ss.23-31, 2015 (SCI-Expanded, Scopus)
2015
201527. Pioglitazonun Metabolik Sendromlu Sıçan Kalp Fonksiyonuna Etkisinin Elektrofizyolojik Yöntemlerle İncelenmesi
DURAK A., TUTAR SELÇUK M. F., OLĞAR Y., OKATAN E. N., DEĞİRMENCİ S., aksu s., et al.
Ankara Üniversitesi Tıp Fakültesi Mecmuası , 2015 (TRDizin)
2014
201428. Beta-blocker timolol alleviates hyperglycemia-induced cardiac damage via inhibition of endoplasmic reticulum stress
ÇİÇEK F., Toy A., TUNCAY E., CAN B., Turan B.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
, cilt.46, sa.5, ss.377-387, 2014 (SCI-Expanded, Scopus)
2014
201429. Enhancement of Cellular Antioxidant-Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn2+ and Ca2+ and Prevention of RyR2-Leak in Hyperglycemic Cardiomyocytes
TUNCAY E., Okatan E. N., Toy A., Turan B.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
, cilt.2014, 2014 (SCI-Expanded, Scopus)
Desteklenen Projeler
2020 - 2021
2020 - 2021Metabolik Sendromlu Sıçan Kalp Fonksiyon Bozukluğunda STIM1 ve ORAI1 Aracılarının Rolünün İncelenmesi
TÜBİTAK Projesi , 1002 - Hızlı Destek Programı
DURAK A. (Yürütücü)