Can PCNA and LIM15 gene expression levels predict sperm retrieval success in men with non-obstructive azoospermia?

Ibis M. A., AYDOS K., Baltaci V., Aktuna S., YAMAN M. Ö.

REVISTA INTERNACIONAL DE ANDROLOGIA, cilt.20, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1016/j.androl.2021.04.002
  • Dergi Adı: REVISTA INTERNACIONAL DE ANDROLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, DIALNET
  • Anahtar Kelimeler: Azoospermia, LIM15, Microdissection testicular sperm extraction, PCNA, Sperm retrieval, CELL NUCLEAR ANTIGEN, TESTICULAR VOLUME, EXTRACTION, DMC1, PROLIFERATION, TESE
  • Ankara Üniversitesi Adresli: Evet

Özet

Introduction and objectives: It is necessary to be able to predict sperm retrieval before microdissection testicular sperm extraction (mTESE) in azoospermic men. This study established the importance of proliferating cell nuclear antigen (PCNA) and LIM15 gene expression levels in predicting the success of sperm retrieval by mTESE.