Can PCNA and LIM15 gene expression levels predict sperm retrieval success in men with non-obstructive azoospermia?

Ibis, MUHAMMED; AYDOS, KAAN; Baltaci, Volkan; Aktuna, Suleyman; YAMAN, MUHİDDİN

doi:10.1016/j.androl.2021.04.002

Can PCNA and LIM15 gene expression levels predict sperm retrieval success in men with non-obstructive azoospermia?

Ibis M. A., AYDOS K., Baltaci V., Aktuna S., YAMAN M. Ö.

REVISTA INTERNACIONAL DE ANDROLOGIA, vol.20, 2022 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 20
Publication Date: 2022
Doi Number: 10.1016/j.androl.2021.04.002
Journal Name: REVISTA INTERNACIONAL DE ANDROLOGIA
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, DIALNET
Keywords: Azoospermia, LIM15, Microdissection testicular sperm extraction, PCNA, Sperm retrieval, CELL NUCLEAR ANTIGEN, TESTICULAR VOLUME, EXTRACTION, DMC1, PROLIFERATION, TESE
Ankara University Affiliated: Yes

Abstract

Introduction and objectives: It is necessary to be able to predict sperm retrieval before microdissection testicular sperm extraction (mTESE) in azoospermic men. This study established the importance of proliferating cell nuclear antigen (PCNA) and LIM15 gene expression levels in predicting the success of sperm retrieval by mTESE.