Synthesis and antimicrobial activity of some novel furyl and benzimidazole substituted benzyl ethers

Ozel Guven O., ERDOĞAN T., GÖKER A. H., Yildiz S.

JOURNAL OF HETEROCYCLIC CHEMISTRY, cilt.44, sa.3, ss.731-734, 2007 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 3
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1002/jhet.5570440336
  • Dergi Adı: JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.731-734
  • Ankara Üniversitesi Adresli: Evet

Özet

In this study, a series of novel furyl and benzimidazole substituted benzyl ethers were synthesized and evaluated for antibacterial and antifungal activities against S. aureus, Methicillin resistant S. aureus (MRSA), E. coli, C. albicans and C. krusei. Compound 6f and 6h exhibited the most potent anti-bacterial activity with lowest MIC values of 3.12 mu g/mL against S aureus and MRSA, respectively.