Diagnosis and management of malignant tumors of the eyelid, conjunctiva and orbit

Gündüz K., Esmaeli B.

Expert Review of Ophthalmology, cilt.3, sa.1, ss.63-75, 2008 (ESCI, Scopus) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 3 Sayı: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1586/17469899.3.1.63
  • Dergi Adı: Expert Review of Ophthalmology
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.63-75
  • Anahtar Kelimeler: Burkitt's lymphoma, Conjunctival primary and acquired melanosis and melanoma, Kaposi's sarcoma, Lymphoid tumor, Metastatic eyelid tumor, Metastatic orbital tumor, Secondary orbital tumor
  • Ankara Üniversitesi Adresli: Hayır

Özet

Ocular adnexal tumors are relatively rare but require unique diagnostic and treatment considerations given the functional importance of the eye and periocular structures and their unique metastatic behavior. In the following paper, we review the major malignant tumors of the ocular adnexa including the eyelid, conjunctiva and orbit. Frozen section control of the margins and, in selected cases, Mohs microsurgery have decreased the recurrence rate in malignant eyelid tumors. Intraoperative cryotherapy and postoperative topical mitomycin C have similarly contributed to better surgical outcomes in conjunctival malignant tumors including squamous cell carcinoma and malignant melanoma. Immunotherapy with CD20 antibodies is a developing treatment in ocular adnexal lymphomas. © 2008 Future Drugs Ltd.