Effects of low-dose midazolam with propofol in patient-controlled sedation (PCS) for apicectomy

Kucukyavuz Z., Cambazoglu M.

BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, vol.42, no.3, pp.215-220, 2004 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 3
  • Publication Date: 2004
  • Doi Number: 10.1016/j.bjoms.2004.01.005
  • Journal Name: BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.215-220
  • Keywords: patient controlled sedation (PCS), conscious sedation, propofol, midazolam, ELDERLY-PATIENTS, SAFETY, END
  • Ankara University Affiliated: Yes

Abstract

We studied the effects of low-dose midazolam with propofol for patient control sedation (PCS) in 30 healthy (ASA grade 1) patients who were randomly allocated into two equal groups (n = 15 in each). They were given a propofol infusion of 2 mg/kg/h after a bolus dose of 0.7 mg/kg. The second group was given the 2 mg/kg/h propofol infusion after a dose of midazolam 0.03 mg/kg and a bolus dose of propofol 0.7 mg/kg. The standard dose for PCS was propofol 0.2 mg/kg in both groups.