Antimicrobial Activities of New Indole Derivatives Containing 1,2,4-Triazole, 1,3,4-Thiadiazole and Carbothioamide
TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.15, sa.3, ss.291-297, 2018 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 3
- Basım Tarihi: 2018
- Doi Numarası: 10.4274/tjps.55707
- Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.291-297
- Anahtar Kelimeler: Indole, 1,2,4-triazole, 1,3,4-thiadiazole, MRSA, C. krusei, RESISTANT STAPHYLOCOCCUS-AUREUS, NORA EFFLUX PUMP, ANTIFUNGAL ACTIVITY, CANDIDA-KRUSEI, TRIAZOLE, EPIDEMIOLOGY, MECHANISMS, INHIBITORS, AGENTS
- Ankara Üniversitesi Adresli: Evet
Özet
Objectives: In new antimicrobial drug development studies, indole and its derivatives create an important class of compounds. In addition, azoles and their derivatives were recognized to be associated with a variety of biologic activities such as antibacterial and antifungal. In this study antimicrobial activities of some indole derivatives mainly substituted with 1,2,4-triazole, 1,3,4-thiadiazole and hydrazinecarbothioamide were investigated to evaluate their efficacy.