Current Approach to Non-Infectious Pulmonary Complications of Hematopoietic Stem Cell Transplantation

CENGİZ SEVAL G., TOPÇUOĞLU P., DEMİRER T.

BALKAN MEDICAL JOURNAL, cilt.35, sa.2, ss.131-140, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 35 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.4274/balkanmedj.2017.1635
  • Dergi Adı: BALKAN MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.131-140
  • Anahtar Kelimeler: Hematopoietic stem cell transplantation, pulmonary complications, Bronchiolitis Obliterans syndrome, Idiopathic Pneumonia syndrome, BONE-MARROW-TRANSPLANTATION, HIGH-DOSE CHEMOTHERAPY, IDIOPATHIC PNEUMONIA SYNDROME, DIFFUSE ALVEOLAR HEMORRHAGE, OBLITERANS ORGANIZING PNEUMONIA, VERSUS-HOST-DISEASE, TOTAL-BODY IRRADIATION, AIR-FLOW OBSTRUCTION, CONSENSUS DEVELOPMENT PROJECT, CHRONIC MYELOGENOUS LEUKEMIA
  • Ankara Üniversitesi Adresli: Evet

Özet

Hematopoietic stem cell transplantation is an established treatment for patients with a wide range of malignant and nonmalignant conditions. Noninfectious pulmonary complications still remain a leading cause of morbidity and mortality in these patients. Treating hematopoietic stem cell transplantation recipients with noninfectious pulmonary complications is still challenging, and the current treatment armamentarium and strategies are not adequate for patients receiving hematopoietic stem cell transplantation. Further trials are needed for a better description of the pathogenesis and the complete diagnostic criteria as well as for the development of effective therapeutic approaches for the management of noninfectious pulmonary complications of the hematopoietic stem cell transplantation. This review outlines the incidence, risk factors, pathogenesis, and clinical spectrum and discusses the current approaches to the management of noninfectious pulmonary complications of Hematopoietic stem cell transplantation.