What is the impact of PPAR-gamma agonist-rosiglitazone on ovarian reserve after hysterectomy? An experimental study

Gundogdu B., Tapisiz O. L., Dilbaz B., Mulazimoglu S. B., Muftuoglu K. H., Dundar B., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.50, no.5, pp.1399-1408, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 5
  • Publication Date: 2020
  • Doi Number: 10.3906/sag-2002-117
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1399-1408
  • Keywords: Hysterectomy, ovarian reserve, rat, Doppler ultrasonography, PPAR gamma, rosiglitazone, ANTI-MULLERIAN HORMONE, TOTAL ABDOMINAL HYSTERECTOMY, ESTROUS-CYCLE, PREMENOPAUSAL WOMEN, SERUM FSH, EXPRESSION, AGE
  • Ankara University Affiliated: Yes

Abstract

Background/aim: To evaluate the effects of hysterectomy on rat ovaries and the possible protective role of peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist-rosiglitazone against ovarian reserve decrement.