ALIMENTARY PHARMACOLOGY & THERAPEUTICS, cilt.11, sa.6, ss.1059-1066, 1997 (SCI-Expanded)
Background: Misoprostol is known to be effective in stimulating intestinal transit both in healthy individuals and in patients with chronic constipation when evaluated in short-term trials. The aim of this study was to determine the utility of misoprostol in the long-term management of patients with chronic refractory constipation.