Anakinra use during pregnancy: Report of a case with Familial Mediterranean Fever and infertility

Ilgen U., KÜÇÜKŞAHİN O.

EUROPEAN JOURNAL OF RHEUMATOLOGY, vol.4, no.1, pp.66-67, 2017 (ESCI, TRDizin) identifier identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.5152/eurjrheum.2017.16075
  • Journal Name: EUROPEAN JOURNAL OF RHEUMATOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.66-67
  • Keywords: Anakinra, Familial Mediterranean Fever, interleukin, 1 beta, pregnancy
  • Ankara University Affiliated: Yes

Abstract

Familial Mediterranean fever (FMF), affecting people of Mediterranean origin, is an endemic and sometimes problematic disease because of colchicine resistance/intolerance, with relative lack of treatment alternatives, and disease-or treatment-related issues, such as subfertility. Anakinra, being a rational and effective treatment alternative, has no conclusive human pregnancy data. Here we report a case of FMF with infertility who became pregnant with in vitro fertilization (IVF) under treatment with anakinra, along with the pregnancy outcome.