The importance of plasma arginine level and its downstream metabolites in diagnosing prostate cancer

Selvi I., Basar H., BAYDİLLİ N., Murat K., KAYMAZ Ö.

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.51, no.11, pp.1975-1983, 2019 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 11
  • Publication Date: 2019
  • Doi Number: 10.1007/s11255-019-02261-8
  • Journal Name: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1975-1983
  • Keywords: Arginine, Diacetylspermin, Ornithine, Prostate biopsy, Prostate cancer, Tumor marker, ANTIGEN, URINE, MARKERS, N-1,N-12-DIACETYLSPERMINE, N-12-DIACETYLSPERMINE, PREVENTION, BIOMARKER, PROGNOSIS, BREAST, PANEL
  • Ankara University Affiliated: Yes

Abstract

Purpose There is still no certain threshold value of prostate-specific antigen (PSA) for prostate cancer diagnosis. We aimed to investigate the predictive value of arginine and its metabolites for diagnosing prostate cancer in patients with PSA 4-10 ng/ml and evaluate their usefulness as prognostic tumor markers.