Efficacy and safety of topical nimesulide in the treatment of knee Osteoarthritis
JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, cilt.13, sa.5, ss.251-255, 2007 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 5
- Basım Tarihi: 2007
- Doi Numarası: 10.1097/rhu.0b013e318156b85f
- Dergi Adı: JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.251-255
- Anahtar Kelimeler: nimesulide, osteoarthritis, topical administration, CYCLOOXYGENASE ACTIVITY, TURKISH VERSION, DOUBLE-BLIND, PHARMACOKINETICS, TRIAL, GEL
- Ankara Üniversitesi Adresli: Evet
Özet
Background: Osteoarthritis (OA) affects mainly older people who are more sensitive to adverse effects of classic nonsteroidal antiinflammatory drugs. Recent publications indicate that topically applied nonsteroidal anti-inflammatory drugs are effective and much safer than their oral analogues.