Efficacy and safety of topical nimesulide in the treatment of knee Osteoarthritis

Erguen H., Kuelcue D., Kutlay Ş., Bodur H., Tulunay F. C.

JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, cilt.13, sa.5, ss.251-255, 2007 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 5
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1097/rhu.0b013e318156b85f
  • Dergi Adı: JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.251-255
  • Anahtar Kelimeler: nimesulide, osteoarthritis, topical administration, CYCLOOXYGENASE ACTIVITY, TURKISH VERSION, DOUBLE-BLIND, PHARMACOKINETICS, TRIAL, GEL
  • Ankara Üniversitesi Adresli: Evet

Özet

Background: Osteoarthritis (OA) affects mainly older people who are more sensitive to adverse effects of classic nonsteroidal antiinflammatory drugs. Recent publications indicate that topically applied nonsteroidal anti-inflammatory drugs are effective and much safer than their oral analogues.