Tumour necrosis factor-alpha, adenosine deaminase and nitric oxide levels in cattle babesiosis before and after treatment

Kontas T., SALMANOĞLU B.

BULLETIN OF THE VETERINARY INSTITUTE IN PULAWY, vol.50, no.4, pp.485-487, 2006 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 4
  • Publication Date: 2006
  • Journal Name: BULLETIN OF THE VETERINARY INSTITUTE IN PULAWY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.485-487
  • Keywords: cattle, babesiosis, tumour necrosis factor-alpha, nitric oxide, adenosine deaminase, BOVINE MONONUCLEAR PHAGOCYTES, IFN-GAMMA, IN-VITRO, MACROPHAGES, PARASITE
  • Ankara University Affiliated: Yes

Abstract

Changes in serum tumor necrosis factor-alpha (TNF-alpha), nitric oxide (NO), and adenosine deaminase (ADA) levels in cattle babesiosis before and after treatment with diminazene aceturate were determined. Before treatment, TNF-alpha, NO, and ADA levels were found to be 71.93 pg/ml, 50.03 mu mol/L, 70.18 IU/L, respectively. These levels were significantly higher than those in the control group. After the treatment, the levels Of the compounds significantly decreased. In Conclusion, besides TNF-alpha and NO, ADA can also be a predictive and sensitive parameter in the diagnosis and prognosis of babesiosis.