Intrinsically Conductive Polymer Nanocomposites for Cellular Applications

Lalegül Ülker Ö., Elçin A. E., Elçin Y. M.

CUTTING-EDGE ENABLING TECHNOLOGIES FOR REGENERATIVE MEDICINE, vol.1078, pp.135-153, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 1078
  • Publication Date: 2018
  • Doi Number: 10.1007/978-981-13-0950-2_8
  • Journal Name: CUTTING-EDGE ENABLING TECHNOLOGIES FOR REGENERATIVE MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.135-153
  • Keywords: Intrinsically conductive polymers, Conductive polymer composites, Tissue engineering, Electrical stimulation, SHAPE-DEPENDENT CYTOTOXICITY, MESENCHYMAL STEM-CELLS, ELECTRICAL-STIMULATION, NANOFIBROUS SCAFFOLDS, CONTROLLED-RELEASE, GLUCOSE BIOSENSOR, MECHANICAL-PROPERTIES, POTENTIAL APPLICATION, FIBROUS SCAFFOLD, CARDIAC TISSUE
  • Ankara University Affiliated: Yes

Abstract

Intrinsically conductive polymer nanocomposites have a remarkable potential for cellular applications such as biosensors, drug delivery systems, cell culture systems and tissue engineering biomaterials. Intrinsically conductive polymers transmit electrical stimuli between cells, and induce regeneration of electroactive tissues such as muscle, nerve, bone and heart. However, biocompatibility and processability are common issues for intrinsically conductive polymers. Conductive polymer composites are gaining importance for tissue engineering applications due to their excellent mechanical, electrical, optical and chemical functionalities. Here, we summarize the different types of intrinsically conductive polymers containing electroactive nanocomposite systems. Cellular applications of conductive polymer nanocomposites are also discussed focusing mainly on poly(aniline), poly(pyrrole), poly(3,4-ethylene dioxythiophene) and poly(thiophene).