Intracavernous Injection of Human Umbilical Cord Blood Mononuclear Cells Improves Erectile Dysfunction in Streptozotocin-Induced Diabetic Rats

Cengiz, Tugba; Kaya, ECEM; Oral, Didem; Özakca Gündüz, IŞIL; Bayatli, Nur; Karabay, ARZU; Ensari, Tugba; Karahan, SÜLEYMAN; Yilmaz, Enis; Gür, SERAP

doi:10.1016/j.jsxm.2016.11.314

Intracavernous Injection of Human Umbilical Cord Blood Mononuclear Cells Improves Erectile Dysfunction in Streptozotocin-Induced Diabetic Rats

Cengiz T., Kaya E., Oral D. Y., Özakca Gündüz I., Bayatli N., Karabay A. Z., ...Daha Fazla

JOURNAL OF SEXUAL MEDICINE, cilt.14, sa.1, ss.50-58, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 14 Sayı: 1
Basım Tarihi: 2017
Doi Numarası: 10.1016/j.jsxm.2016.11.314
Dergi Adı: JOURNAL OF SEXUAL MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.50-58
Anahtar Kelimeler: Human Umbilical Cord Blood Mononuclear Cells, Erectile Dysfunction, Diabetes, von Willebrand Factor, Hypoxia Inducible Factor, Intracavernosal Pressure, MESENCHYMAL STEM-CELLS, CORPORA CAVERNOSA RELAXATION, PROGENITOR CELLS, INHIBITION, THERAPY, TRANSPLANTATION, FIBROSIS, DELIVERY, MODEL, ONSET
Ankara Üniversitesi Adresli: Evet

Özet

Introduction: Erectile dysfunction (ED) worsens in men with diabetes. Human umbilical cord blood (HUCB), because of its widespread availability and low immunogenicity, is a valuable source for stem cell-based therapies.