Effectiveness of Tacrolimus in High-Risk Limbal Allo-Graft Transplantation

Yalcindag F. N., Incel O., Oezdemir O.

ANNALS OF OPHTHALMOLOGY, vol.40, no.3-4, pp.152-156, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 3-4
  • Publication Date: 2008
  • Journal Name: ANNALS OF OPHTHALMOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.152-156
  • Ankara University Affiliated: Yes

Abstract

We evaluated the efficacy and safety of tacrolimus in prevention of allograft rejection in high-risk allo-limbal grafts. Six eyes of six patients with severe limbal stem cell deficiency were included. All patients were started 0.1 mg.kg(-1).day(-1) tacrolimus orally 3 days before the surgery. Limbal allo-g raft transplantation for ocular surface reconstruction had a successful outcome with using systemic tacrolimus for immunosuppression.