Antimicrobial activities of N-(2-hydroxy-1-naphthalidene)-amino acid(glycine, alanine, phenylalanine, histidine, tryptophane) Schiff bases and their manganese(III) complexes
BIOMETALS, vol.17, no.2, pp.115-120, 2004 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 17 Issue: 2
- Publication Date: 2004
- Doi Number: 10.1023/b:biom.0000018380.34793.df
- Journal Name: BIOMETALS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.115-120
- Keywords: antifungal activity, antimicrobial activity, manganese (III) complexes, Schiff bases, AMINO-ACIDS, BIOLOGICAL-ACTIVITY, COPPER(II), NICKEL(II), ZINC(II), PALLADIUM(II), ORGANOTIN(IV), COBALT(III)
- Ankara University Affiliated: No
Abstract
The in vitro antibacterial and antifungal activities of five different amino acid Schiff bases derived from the reaction of 2-hydroxy-1-naphthaldehydewith glycine, L-alanine L-phenylalanine, L-histidine, L-tryptophane and the manganese( III) complexes of these bases were investigated. Structures of the Schiff bases were proven by H-1-NMR. In vitro activities against some Gram-positive ( Staphylococcus aureus and Bacillus polymyxa) and Gram-negative ( Escherichia coli) bacteria and the fungus Candida albicans were determined. The antimicrobial activities tended to decrease with the increasing size of the amino acid residues.