Simulation based analysis of He-4, Li-7, Be-8 and B-10 ions for heavy ion therapy


Ekinci F., Bostanci E., Guzel M. S., Dagli O.

INTERNATIONAL JOURNAL OF RADIATION RESEARCH, cilt.21, sa.1, ss.131-137, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 1
  • Basım Tarihi: 2023
  • Doi Numarası: 10.52547/ijrr.21.1.18
  • Dergi Adı: INTERNATIONAL JOURNAL OF RADIATION RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.131-137
  • Anahtar Kelimeler: Heavy ion therapy, Bragg cure, recoil, lateral straggle, phonon., DOSE DISTRIBUTIONS, PARTICLE THERAPY, PROTON, BEAMS, HELIUM, WATER, C-12, CARBON, H-1, ADVANTAGES
  • Ankara Üniversitesi Adresli: Evet

Özet

Background: The therapeutic usage of heavy ions has received much attention due to its advantageous physical and radiobiological assets compared to photon-based therapy. Thanks to these unique properties of heavy ion radiotherapy, it can allow dose increase in tumors while reducing the radiation dose in adjacent normal tissues. Materials and Methods: The main aim of this study is to analyze the LET, recoils, lateral scattering, and phonon energies of selected He-4, Li-7, Be-8 and B-10 heavy ions in the water phantom in the therapeutic energy range. This analysis was performed by using MC based TRIM simulation method of interactions. Results: The main innovation that this study will provide to the literature is not only ionization but also the calculation of recoils, lateral scattering and phonon oscillation resulting from all interactions. According to the calculation results, the largest recoils peak value was found to be 7.957 eV/A-ionx10(3) in the B ion, and it was observed that it formed an average of 88% more recoil peaks than He ion, 53% on average than Li ion and 24% more than Be ion on average. In the lateral scattering, the greatest value occurred in the He ion. It should be noted that He ion produced 42%, 57% and 71% more lateral scattering than Li, Be and B ions respectively. As a result of all these interactions, 32% of the phonon and 68% of the phonon were formed respectively by the recoil interactions. Conclusion: This study includes ionization and all particle-based target interactions.