C6-H Bond Functionalization of Indoles: A New Gate
SYNTHESIS-STUTTGART, sa.21, ss.3417-3433, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Basım Tarihi: 2023
- Doi Numarası: 10.1055/a-2050-4897
- Dergi Adı: SYNTHESIS-STUTTGART
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chemical Abstracts Core, Chimica, Compendex
- Sayfa Sayıları: ss.3417-3433
- Ankara Üniversitesi Adresli: Hayır
Özet
Indoles are valuable precursors in medicinal, bioorganic, and material chemistry and particularly serve as a platform for diversity. However, the scope of the C6-functionalization of indoles was limited until recently. In this short review, we summarize developments in the C6-functionalization reactions of indoles involving transition-metal-cat-alyzed functionalization and Brunsted and Lewis acid catalyzed process -es. The regioselectivity is controlled by remote-C-H activation and hy-drogen bond formation. 1 Introduction 2 Transition-Metal-Catalyzed Functionalization 3 Acid-Catalyzed Processes 4 Conclusion