Ankara Üniversitesi veteriner fakültesi dergisi, cilt.46, sa.1, ss.105-114, 2000 (Hakemli Dergi)
This study was carried out umler li~ht-, ./lııoresccncc - aııd
e1ecfrolı microscopy to investigate the efreds ol a/latoxin Bı in feeds on chicks'
li ı'er and its re/ation with vitamin A metabolism,
Thirtv chich were used throughout the study. Dil red o dye was used/in- thc
demonstration olfats in the liver and gold impregnation was IJellinmed to shmı'
the perisinl/soidal cells' localisation,
Results showed that there wcre /i)cal areas ot.tiJ! depe/7(ling on exccss .tat
accumulation in the helHJ!ocytes, endothelial lining eel Is j,vhich comfJose thc 1}(I,lic
structure ot sinusoids had negative ef{eus arising .ti'Ofn disorganiaJ!iolı olliver
filates, Kupfrer eclls were deereased and their phagocytic abilities j,vas reduced.
Depmding on decrease ol perisinusoidal cclls, liver \1'as regressed the abilitv to
s/ore vi/mniıı A.