Correlation between tissue levels of carboxy-terminal propeptide of type I procollagen and clinicopathological characteristics in human colorectal cancer

EROĞLU A., Demirci S., Akbay A., Sunguroglu K.

HEPATO-GASTROENTEROLOGY, cilt.47, sa.34, ss.1006-1010, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 34
  • Basım Tarihi: 2000
  • Dergi Adı: HEPATO-GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.1006-1010
  • Anahtar Kelimeler: colorectal cancer, type I procollagen, prognosis, EXTRACELLULAR-MATRIX, BONE METASTASES, TUMOR INVASION, COLLAGEN DEGRADATION, BREAST-CANCER, CARCINOMA, MARKERS, METABOLITES, PINP, PICP
  • Ankara Üniversitesi Adresli: Evet

Özet

Background/Aims: Type 1 collagen is the most abundant protein in the human body and a major constituent of the interstitial connective tissue. However, little is known about carboxy-terminal propeptide of type I procollagen (PICP) expression in human colorectal tumor tissues. We therefore evaluated the concentrations of PICP in colorectal tumor tissue as well as surrounding normal tissues and examined the relationship between its level and clinicopathological variables.