Autologous platelet collection and storage to support thrombocytopenia in a leukemia patient with platelet alloimmunization undergoing chemotherapy

YÜKSEL M., Arat M., ARSLAN Ö., BEKSAÇ M., İLHAN O.

Turkish Journal of Haematology, cilt.20, sa.4, ss.233-236, 2003 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 4
  • Basım Tarihi: 2003
  • Dergi Adı: Turkish Journal of Haematology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.233-236
  • Anahtar Kelimeler: Allogeneic, Blood transfusion autologous, Immunization, Platelet, Transfusion
  • Ankara Üniversitesi Adresli: Evet

Özet

Platelet alloimmunization occurs frequently in multitransfused patients. To prevent the posttransfusion complications donor white blood cells (WBCs) must be removed from the platelet concentrates (PC). But sometimes the centrifugation and filtration of WBC is not enough and in such conditions HLA-matched PC are recommended. Cryopreservation of autologous PC offers a potential solution to this problem. We investigated the feasibility of supporting the aplastic period after chemotherapy in a 54-year-old leukemia patient with autologous platelets collected by apheresis and cryopreserved. Our case report demonstrates that autologous apheresis platelet transfusion might be a feasible approach to high risk patients with bleeding tendencies.