Applying the miniaturization technologies for biosensor design

Derkuş B.

BIOSENSORS & BIOELECTRONICS, cilt.79, ss.901-913, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 79
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.bios.2016.01.033
  • Dergi Adı: BIOSENSORS & BIOELECTRONICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.901-913
  • Anahtar Kelimeler: Miniaturization, Microtechnology, Nanotechnology, Micropatterning, Nanopatterning, Microfluidics, MEMs, MEDIATED ISOTHERMAL AMPLIFICATION, REAL-TIME, MICROFLUIDIC CHIP, STENCIL LITHOGRAPHY, RAPID DETECTION, WHOLE-BLOOD, MASS SENSOR, SYSTEM, CELLS, MEMS
  • Ankara Üniversitesi Adresli: Hayır

Özet

Microengineering technologies give us some opportunities in developing high-tech sensing systems that operate with low volumes of samples, integrates one or more laboratory functions on a single substrate, and enables automation. These millimetric sized devices can be produced for only a few dollars, which makes them promising candidates for mass-production. Besides electron beam lithography, stencil lithography, nano-imprint lithography or dip pen lithography, basic photolithography is the technique which is extensively used for the design of microengineered sensing systems. This technique has some advantages such as easy-to-manufacture, do not require expensive instrumentation, and allow creation of lower micron-sized patterns. In this review, it has been focused on three different type of micro engineered sensing devices which are developed using micro/nano-patterning techniques, microfluidic technology, and microelectromechanics system based technology. (C) 2016 Elsevier B.V. All rights reserved.