Antioxidant and antiapoptotic effects of darbepoetin-alpha against traumatic brain injury in rats

Kertmen H., Gurer B., Yilmaz E. R., Kanat M. A., Arikok A. T., ERGÜDER B. İ., ...Daha Fazla

ARCHIVES OF MEDICAL SCIENCE, cilt.11, sa.5, ss.1119-1128, 2015 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 5
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5114/aoms.2015.54869
  • Dergi Adı: ARCHIVES OF MEDICAL SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1119-1128
  • Anahtar Kelimeler: antiapoptosis, antioxidation, darbepoetin-alpha, methylprednisolone, neuroprotection, rat, traumatic brain injury, ISCHEMIA-REPERFUSION INJURY, NITRIC-OXIDE SYNTHASE, SPINAL-CORD ISCHEMIA, LIPID-PEROXIDATION, OXIDATIVE STRESS, CEREBRAL-ISCHEMIA, XANTHINE-OXIDASE, IMPACT INJURY, FREE-RADICALS, HEAD-INJURY
  • Ankara Üniversitesi Adresli: Evet

Özet

Introduction: In this study, we tried to determine whether darbepoetin-alpha would protect the brain from oxidative stress and apoptosis in a rat traumatic brain injury model.