Pentoxifylline use in dermatology

Çakmak S. K., ÇAKMAK A., Gönül M., Kiliç A., Gül Ü.

Inflammation and Allergy - Drug Targets, cilt.11, sa.6, ss.422-432, 2012 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.2174/187152812803590028
  • Dergi Adı: Inflammation and Allergy - Drug Targets
  • Derginin Tarandığı İndeksler: Scopus, Biotechnology Research Abstracts
  • Sayfa Sayıları: ss.422-432
  • Anahtar Kelimeler: Dermatology, Disorder, Pentoxifylline, Treatment, Tumor necrosis factor-α inhibitor
  • Ankara Üniversitesi Adresli: Evet

Özet

Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug. Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline might be efficacious in a wide spectrum of skin diseases. This article focuses on the use of pentoxifylline which is a safe and cheap drug in various dermatological disorders. © 2012 Bentham Science Publishers.