Nitric oxide metabolism in cancerous and non-cancerous oral gingivomucosal tissues: possible implications of nitric oxide in cancer process

Avci A., Tuezuener-Oencuel A. M., Goekcan M. K., Namuslu M., Oeztuerk A., Durak I.

JOURNAL OF ORAL PATHOLOGY & MEDICINE, cilt.38, sa.3, ss.304-306, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1111/j.1600-0714.2008.00719.x
  • Dergi Adı: JOURNAL OF ORAL PATHOLOGY & MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.304-306
  • Anahtar Kelimeler: nitric oxide, oral cancer, SYNTHASE ACTIVITY, CELL CARCINOMA, EXPRESSION, ANGIOGENESIS, PROGRESSION, TUMORS, NECK, HEAD
  • Ankara Üniversitesi Adresli: Evet

Özet

Nitric oxide (NO) is a molecule that plays various roles in the body tissues. NO plays important roles in vasodilatation, platelet aggregation, cytokine stimulation, neurotransmission, immune function, etc. NO also exerts dual functions as an oxidant and antioxidant substance depending on its concentrations and environmental conditions. In this study, we aimed to examine possible correlation between NO levels and NO synthase (NOS) activity in the patients with oral cancer.