Research Information System
JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, vol.98, no.4, pp.655-657, 2006 (SCI-Expanded)
Chylomicronemia syndrome is a rare disorder characterized by the presence of chylomicrons in the fasting state. An acute and potentially life-threatening complication of chylomicronemic syndrome is severe acute pancreatitis. We report a case of a 24-year-old primigrovida with severe hypertriglyceridemio-induced poncreatitis. We reviewed the clinical course and treatment of hypertriglyceridemia-induced pancreatitis, She was admitted in the 37th week of gestation with severe abdominal pain, which was radiating to the back, and having uterine contractions. Cesarean delivery was performed under spinal anesthesia, and a healthy male infant was born. Introoperative findings included milky peritoneal fluid collection. Elevated pancreatic enzymes with significant hypertriglyceridemic (10,092 mg/dL) suggesting acute pancreatitis were also found on chemical analysis. The diagnosis of acute pancreatitis was confirmed by computed tomography scan. Treatment with continuous intravenous insulin-glucose, cessation of oral intake, and nosogastric decompression-dramatically decreased the triglyceride levels to 608 mg/dL within five days. She was discharged as symptom free with strict dietary intervention after 10 days. Intravenous insulin is a low-cost and effective alternative treatment in hypertriglyceridemia-induced pancreatitis during pregnancy. To our knowledge, such a high triglyceride level has not previously been reported in pregnancy.