Southern Medical Journal, cilt.87, sa.11, ss.1186-1189, 1994 (SCI-Expanded)
A 66-year-old woman presented clinical findings of Eaton-Lambert (myasthenic) syndrome (ELS). Fifteen months later, large-cell pulmonary carcinoma was detected. After systemic chemotherapy and radiotherapy, the tumor regressed and neurologic function improved. Although ELS is usually associated with pulmonary small-cell carcinoma, a minority of tumors are of squamous or glandular differentiation. We believe this is the first case report of ELS associated with large-cell neuroendocrine carcinoma in the English language literature, and it illustrates the importance of an aggressive approach to diagnosis and treatment. © 1994 Southern Medical Association.