Akademik Veri Yönetim Sistemi
ISAM 2024 CONGRESS, İstanbul, Türkiye, 5 - 08 Eylül 2024, ss.28, (Özet Bildiri)
Introduction/Objectives: Addiction represents a pathological condition characterized by substantial impairments in fulfilling individual and environmental obligations, significantly encroaching upon various essential life pursuits. The use of substances can precipitate acute and chronic neurological and cognitive impairments in individuals. Hence, research endeavors have been directed towards comprehensive investigations employing diverse imaging modalities over extensive periods to enhance the comprehension of the neurobiological impacts of addiction and substance use. The exploration of both the etiology of addiction and the neural alterations following substance use has been central to the aims of these investigations. Specifically, studies shaped by a neuroscientific perspective aim to furnish researchers, clinicians, and professionals with enhanced insights into the physiological and chemical dimensions underpinning addictive processes, thereby facilitating the illumination of addiction intervention programs. Furthermore, these investigations seek to illuminate topics such as relapse prediction and the therapeutic evaluation of non-invasive brain stimulations, in addition to elucidating the development of addiction. In the perspective of current clinical applications, the present and ongoingly refined techniques utilized for investigating the relationship between addiction and neural circuits will be delineated. Furthermore, alongside the historical evolution of these aforementioned methods, the discussion will encompass how their advantages and disadvantages can be adapted to address issues originating from the central nervous system in addiction. Methods: This study was structured as a review article, and articles were compiled by conducting searches across six distinct electronic databases (PubMed, Scopus, Web of Science, Google Scholar, ScienceDirect, BMC Psychiatry) using keywords related to addiction, substance use disorder, and neuroimaging. The search encompassed articles published from 2014 to 2024. Conclusions: Neuroimaging studies make significant contributions to clinical practice by facilitating the quantification of the impacts of addiction and its treatments, identifying individuals at heightened risk for addiction development, and furnishing neurobiological and functional indicators that can aid in guiding these individuals towards the most efficacious treatments. Keywords: Addiction, Substance use disorder, Neuroimaging