Synthesis and antimicrobial activity of some new 3-substituted benzyl-5-(4-chloro-2-piperidin-1-ylthiazole-5-yl-methylene)-thiazolidine-2,4-dione derivatives
TURKISH JOURNAL OF CHEMISTRY, cilt.30, sa.3, ss.355-360, 2006 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 30 Sayı: 3
- Basım Tarihi: 2006
- Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.355-360
- Anahtar Kelimeler: thiazolidine-2,4-diones, thiazole derivatives, antimicrobial activities
- Ankara Üniversitesi Adresli: Evet
Özet
A new series of thiazolyl thiazolidine-2,4-dione (Va-f) were synthesized and their structures were elucidated by IR, H-1-NMR, mass spectra and elementary analysis. The synthesized compounds were tested for their antimicrobial activities against Candida albicans, Staphylococcus aureus, Bacillus subtilis and Escherichia coli. Compounds Va-b, Vd-f showed high activity against Escherichia coli comparable to ampicillin.