Synthesis and antimicrobial activity of some new 3-substituted benzyl-5-(4-chloro-2-piperidin-1-ylthiazole-5-yl-methylene)-thiazolidine-2,4-dione derivatives

Unlusoy M., Dundar O. B., Altanlar N., Ertan R.

TURKISH JOURNAL OF CHEMISTRY, cilt.30, sa.3, ss.355-360, 2006 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 3
  • Basım Tarihi: 2006
  • Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.355-360
  • Anahtar Kelimeler: thiazolidine-2,4-diones, thiazole derivatives, antimicrobial activities
  • Ankara Üniversitesi Adresli: Evet

Özet

A new series of thiazolyl thiazolidine-2,4-dione (Va-f) were synthesized and their structures were elucidated by IR, H-1-NMR, mass spectra and elementary analysis. The synthesized compounds were tested for their antimicrobial activities against Candida albicans, Staphylococcus aureus, Bacillus subtilis and Escherichia coli. Compounds Va-b, Vd-f showed high activity against Escherichia coli comparable to ampicillin.