Validation of Peptest (TM) in Patients with Gastro-Esophageal Reflux Disease and Laryngopharyngeal Reflux Undergoing Impedance Testing

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BOR S., Capanoglu D., VARDAR R., Woodcock A. D., Fisher J., Dettmar P. W.

JOURNAL OF GASTROINTESTINAL AND LIVER DISEASES, vol.28, no.4, pp.383-387, 2019 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.15403/jgld-335
  • Journal Name: JOURNAL OF GASTROINTESTINAL AND LIVER DISEASES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.383-387
  • Keywords: gastro-esophageal reflux disease, laryngopharyngeal reflux, multichannel intraluminal impedance, pepsin, Peptest (TM), NORMAL VALUES, PEPSIN, PH, RELIABILITY, VALIDITY, DIAGNOSIS, SYMPTOMS, SALIVA
  • Open Archive Collection: AVESIS Open Access Collection
  • Ankara University Affiliated: No

Abstract

Background & Aims: Pepsin in the gastric refluxate is a marker for a prior reflux event and rapid detection might be achieved using the Peptest (TM), an in vitro diagnostic medical device. The aim of this study was to validate the use of Peptest (TM) to reliably diagnose reflux in patients with gastro-esophageal reflux disease (GERD) and laryngopharyngeal reflux (LPR) disease diagnosed with multichannel intraluminal impedance/pHmetry (MII-pH).