KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.15, sa.4, ss.543-546, 2009 (SCI-Expanded)
In the present study serum homocysteine levels were determined in female cats diagnosed as chronic renal failure (CRF) and its correlation with serum urea and creatinin levels were investigated. The study was conducted on a total of 21 female cats (13 diseased and 8 healthy cats). admitted to the Department of Internal Medicine Clinics, School of Veterinary Medicine, University of Ankara, diagnosed as CRF upon clinical examination and laboratory results. Serum samples were retrieved from cats and urea, creatinin and homocysteine levels were determined. In healthy cats, urea. creatinin and homocysteine levels were 37.74 +/- 4.47 mg/dl. 1.46 +/- 0.14 mg/dl and 13.03 +/- 2.81 mu mol/L. and in cats with CRF 278 81 +/- 45 68 mg/dl. 6.14 +/- 0.80 mg/dl and 41.68 +/- 9.97 mu mol/L. respectively. In conclusion. determination of serum homocysteine levels in CRF cases occuring in cats could significantly contribute to the early diagnosis of the disease. Furthermore, to the best of our knowledge there is no such study conducted about this subject. it could also contribute for the further studies related to CRF.