Intractable colitis associated with chronic granulomatous disease in a young girl

Yaman A., KULOĞLU Z., DOĞU E. F., İKİNCİOĞULLARI K. A., ENSARİ A., ÇİFTCİ E., ...Daha Fazla

TURKISH JOURNAL OF PEDIATRICS, cilt.57, sa.2, ss.189-191, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 2
  • Basım Tarihi: 2015
  • Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.189-191
  • Anahtar Kelimeler: chronic granulomatous disease, colitis, children
  • Ankara Üniversitesi Adresli: Evet

Özet

Chronic granulomatous disease (CGD) is an autosomal recessive or X-linked disorder caused by NADPH oxidase deficiency leading to an impaired ability of reactive superoxide anion and metabolite formation and recurring severe bacterial and fungal infections, with a high mortality rate. Diarrhea, colitis, ileus, perirectal abscess formation and anal fissures are reported gastro-intestinal findings in these patients. We report a case of intractable colitis associated with CGD in a young girl.