BRITISH JOURNAL OF DERMATOLOGY, vol.185, no.6, pp.1209-1220, 2021 (SCI-Expanded)
Background Behcet disease (BD) presents with lymphocytic and neutrophilic vasculitis of unknown aetiology. HLA-B*51, the endoplasmic reticulum aminopeptidase 1 (ERAP1), and interleukin 23 receptor (IL23R)/IL12R are genetic risk factors. IL-23 regulates IL-17A, which controls the recruitment and activation of neutrophils.