Intravenous iron therapy impact on transfusions in coronary artery bypass patients with preoperative iron deficiency anemia


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Sert Y. K., BERMEDE A. O., GÜVEN A., Safak B., Koroglu M.

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, sa.9, ss.600-603, 2024 (ESCI) identifier

Özet

Aim: This study aimed to investigate the effect of preoperative intravenous iron therapy on blood and blood products transfusion in patients with preoperative iron deficiency anemia and coronary artery bypass graft surgery. Material and Methods: The records of 86 patients who underwent isolated CABG surgery at the Ankara University Faculty of Medicine Heart Center between 2019 and 2021 were retrospectively analyzed. A total of 43 patients with iron deficiency anemia who underwent preoperative IV iron therapy and those who did not undergo IV iron therapy were included in the study. Hemoglobin (Hb), ferritin, and serum iron levels were examined in the preoperative and postoperative periods. Results: There was no difference in preoperative Hb levels, ferritin, or preoperative serum iron levels between the groups receiving IV therapy and those not receiving IV therapy (p = 0.75, p = 0.06, p = 0.71). There was no significant difference between the two groups in terms of early postoperative Hb and discharge Hb (p = 0.28; p = 0.1; p > 0.05). Hb values were found to be significantly higher in those who received IV iron therapy at the follow-up one month later (12.84 +/- 1.52 and 11.6 +/- 1.47, p<0.001). There was no significant relationship between the amount of erythrocyte suspension used. Discussion: It can be said that it would be more beneficial to administer IV iron therapy and wait 3-4 weeks for patients who will undergo elective surgery with iron deficiency anemia in the pre-operative period. IV iron therapy must be applied to the patient immediately before urgent operations, such as CABG operations.