The longest infectious virus shedding in a child infected with the G614 strain of SARS-COV-2

Bal Z. S., ÖZKUL A., Bilen M., Kurugol Z., Ozkinay F.

Pediatric Infectious Disease Journal, cilt.40, sa.7, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 7
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1097/inf.0000000000003158
  • Dergi Adı: Pediatric Infectious Disease Journal
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: SARS-CoV-2, COVID-19, infectious virus, shedding, child
  • Ankara Üniversitesi Adresli: Evet

Özet

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.COVID-19 spread globally and caused over 97 million cases with more than 2 million deaths. There is still ongoing discussion on the duration of infectious interval SARS-CoV-2 infection. Symptomatic children had longer virus shedding and there are some reports of prolonged infectious virus shedding in adults particularly patients having an immunocompromised status. A missense mutation, D614G, in the spike protein of SARSCoV-2, which has emerged as a predominant clade in Europe and is spreading worldwide that can result in higher viral loads in patients. Herein, we described the longest infectious virus shedding in a previously healthy child infected with SARS-CoV-2 expressing spike D614G substitution.