Chemoresistance in Malignant Intracranial Tumors: Longer Survival with Negative MDR1 Expression

Ezgu, Mehmet; Kural, Cahit; Simsek, Gulcin; Kaygin, Pinar; OĞUZTÜZÜN, SERPİL; Kirik, Alparslan; Yasar, Soner; KÖSE, GÜLŞAH; YILMAZ SARIALTIN, SEZEN; ÇOBAN, TÜLAY; KUL, OĞUZ

doi:10.5137/1019-5149.jtn.29819-20.3

Chemoresistance in Malignant Intracranial Tumors: Longer Survival with Negative MDR1 Expression

Ezgu M. C., Kural C., Simsek G. G., Kaygin P., OĞUZTÜZÜN S., Kirik A., ...Daha Fazla

TURKISH NEUROSURGERY, cilt.31, sa.3, ss.447-459, 2021 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 31 Sayı: 3
Basım Tarihi: 2021
Doi Numarası: 10.5137/1019-5149.jtn.29819-20.3
Dergi Adı: TURKISH NEUROSURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
Sayfa Sayıları: ss.447-459
Anahtar Kelimeler: Brain, Tumor, Glutathione S-transferase, Cytochrome p450, Multidrug resistance, GLUTATHIONE S-TRANSFERASES, GENETIC POLYMORPHISMS, GENOTYPES, RISK, MRP1
Ankara Üniversitesi Adresli: Evet

Özet

AIM: To analyze the Glutathione S-transferase (GST)-P, GST-M, cytochrome p450 (CYP)1-A1, CYP1-B1, and multidrug resistance (MDR)-1 expressions in malignant intracranial tumor (ICT)s, and to elicit their role on patient survival.