Determination of Vulpinic Acid Effect on Apoptosis and mRNA Expression Levels in Breast Cancer Cell Lines

Kilic N., Aras S., CANSARAN DUMAN D.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.18, sa.14, ss.2032-2041, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 14
  • Basım Tarihi: 2018
  • Doi Numarası: 10.2174/1871520618666180903101803
  • Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2032-2041
  • Anahtar Kelimeler: Vulpinic acid, breast cancer, apoptosis, qRT-PCR, Lichen secondary metabolites, SK-BR-3 cell lines, USNIC ACID, LICHEN, METABOLITES, MEMBRANE, PROFILES, GROWTH
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Breast cancer is one of the most common diseases among women worldwide and it is characterized by a high ratio of malignancy and metastasis and low rate of survival of patients. Due to limited treatment options, the discovery of alternative therapeutic agents and clarifying the molecular mechanism of breast cancer development may offer new hope for its treatment. Lichen secondary metabolites may be one of these therapeutic agents.