The trinity of matrix metalloproteinases, inflammation, and cancer: A literature review of recent updates

Ozkan E., BAKAR ATEŞ F.

Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry, cilt.19, sa.3, ss.206-221, 2020 (Scopus) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 19 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.2174/1871523018666191023141807
  • Dergi Adı: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry
  • Derginin Tarandığı İndeksler: Scopus, Agricultural & Environmental Science Database, BIOSIS, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.206-221
  • Anahtar Kelimeler: Cancer, Cytokine, Inflammation, Inhibitors, Matrix metalloproteinase, TIMP
  • Ankara Üniversitesi Adresli: Evet

Özet

© 2020 Bentham Science Publishers.The critical link between cancer and inflammation has been known for many years. This complex network was further complexed by revealing the association of the matrix metalloproteinase family members with inflammatory cytokines, which were previously known to be responsible for the development of metastasis. This article summarizes the current studies which evaluate the relationship between cancer and inflammatory microenvironment as well as the roles of MMPs on invasion and metastasis together.